Aloin Chemical Properties

Melting point:

148°C

Boiling point:

456.17°C (rough estimate)

Density 

1.3028 (rough estimate)

refractive index 

1.6230 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

solubility 

pyridine: 50 mg/mL, clear, dark red

form 

Solid

pka

7.12±0.40(Predicted)

color 

Yellow needles from EtOH

BRN 

6077558

Stability:

Stable, but light sensitive. Incompatible with bases, strong oxidizing agents. Combustible.

InChIKey

AFHJQYHRLPMKHU-WEZNYRQKSA-N

LogP

0.944 (est)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

LZ6520000

F 

8

HS Code 

29329990

Toxicity

LDLo orl-cat: 500 mg/kg HBAMAK 4,1298,35

MSDS

• Language:English Provider:10-beta-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
• Language:English Provider:SigmaAldrich

Aloin Usage And Synthesis

Chemical Properties

lemon yellow crystalline powder

Uses

Aloin is a naturally occurring substance found in various Aloe plant species. Aloin was originally used as a laxative in the treatment of constipation. Recent studies have investigated Aloin as an ant ineoplastic agent that enhances melanogenesis and transglutaminase activity.

Uses

Aloe exudant, used as a stimulant-laxative

Definition

ChEBI: A C-glycosyl compound that is beta-D-glucopyranose in which the anomeric hydroxy group is replaced by a 4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl moiety (the 9S d astereoisomer).

Safety Profile

Poison by subcutaneous andintravenous routes. Moderately toxic by ingestion. Whenheated to decomposition it emits acrid smoke and fumes.A carthartic and purgative.

Purification Methods

Aloin forms the monohydrate as lemon yellow crystals on crystallisation from H2O (450g/1.5L) which has a lower m ~70-80o than the anhydrous substance. [Cahn & Simonsen J Chem Soc 2573 1932, Hay & Haynes J Chem Soc 3141 1956.]

Aloin(1415-73-2)Related Product Information

• Emodin-3-methyl ether
• Aloe emodin
• Tris(hydroxymethyl)nitromethane
• Emodin
• Solvent Red 43
• Aloin B
• ALOESIN
• 2,2'-DIHYDROXYBENZOPHENONE
• 1,1-DIPHENYLHEXANE
• 1,1-DIPHENYL-2-PROPANOL
• ALOIN,POWDER,ALOIN, CRUDE
• Ellagic acid
• Aloin 8-O-β-D-glucopyranoside
• 5-ISOPROPYL-3-METHYLPHENOL
• 3,3-Diphenylpropanol
• Aloin
• (R)-(-)-1,1-DIPHENYL-2-PROPANOL
• 2,5-DIMETHYLPHENETHYL ALCOHOL