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2-Ethoxy-5-fluoro-1H-pyrimidin-4-one

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2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Basic information

Product Name:
2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
Synonyms:
  • ETHOXYFLUOROURACIL
  • 5-FLUORO-2-ETHOXY-4(1H)-PYRIMIDINONE
  • 5-FLUORO-2-ETHOXY-4-PYRIMIDINONE
  • 2-ethoxy-5-fluoro-1h-pyrimidin-4-one
  • 2-ETHOXY-5-FLUORO-2,3-DIHYDROPYRIMIDIN-4(1H)-ONE
  • 2-ETHOXY-5-FLUORO-4(3H)-PYRIMIDINONE
  • 2-ETHOXY-5-FLUORO-4-HYDROXYPYRIMIDINE
  • 2-ETHOXY-5-FLUORO-4-PYRIMIDINONE
CAS:
56177-80-1
MF:
C6H7FN2O2
MW:
158.13
EINECS:
260-029-1
Product Categories:
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyridines, Pyrimidines, Purines and Pteredines
  • INTERMEDIATESOFFINASTERIDE
  • Pyrimidine
  • Pyrimidines
Mol File:
56177-80-1.mol
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2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Chemical Properties

Melting point:
180-184 °C (lit.)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
6.45±0.50(Predicted)
Water Solubility 
2g/L at 20℃
InChIKey
XREDGJFKPWBNRQ-UHFFFAOYSA-N
LogP
-0.96 at 25℃
CAS DataBase Reference
56177-80-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29335990

MSDS

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2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Usage And Synthesis

Uses

Ethoxy-5-fluoro-4(3H)-pyrimidinone (Fluorouracil EP Impurity F) is a derivative of 5-fluorouracil (3C,15N2 labelled, F596002) which is a potent antineoplastic agent in clinical use.

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