Chloropyramine Chemical Properties

Melting point:

25°C

Boiling point:

bp0.2 154-155°

Density 

1.1031 (rough estimate)

refractive index 

1.6010 (estimate)

pka

9.00±0.28(Predicted)

NIST Chemistry Reference

Chloropyramine(59-32-5)

Chloropyramine Usage And Synthesis

Uses

Chloropyramine is used for allergic dermatosis, allergic rhinitis and conjunctivitis, for drug-induced allergies, in the beginning stages of bronchial asthma, eczema, neurodermatitis, contact dermatitis, and toxicodermia. It also exhibits a sedative effect. Synonyms of this drug are suprastin, chlortripelenamine, and synopen.

Definition

ChEBI: N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridinyl)ethane-1,2-diamine is an aminopyridine.

Synthesis

Chloropyramine, N-(4-chlorobenzyl)-N??,N??-dimethyl-N-2-pyridylethylenediamine (16.1.9), is synthesized in a somewhat different manner, which is by reacting 2-brompyridine with N-(4-chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8). N-(4-Chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8), in turn, is synthesized by condensation of 4-chlorobenzaldehyde c N,N-dimethylethylenediamine with subsequent reduction of the imine group.

Chloropyramine(59-32-5)Related Product Information

• Forchlorfenuron
• Clopidogrel
• 2,6-Lutidine
• ISOXADIFEN-ETHYL
• Dimethyl sulfide
• Dimethyl fumarate
• Niclosamide
• Sulfachoropyrazine sodium
• Ethyl acetate
• Clopidogrel hydrogen sulfate
• 3-Dimethylaminopropylamine
• 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide
• Ethanol
• 4-Dimethylaminopyridine
• Trinexapac-ethyl
• Ethyl acrylate
• Fluroxypyr
• Pyridine