2'-Fluoroacetophenone Chemical Properties

Melting point:

26-27C

Boiling point:

187-189 °C(lit.)

Density 

1.137 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.507(lit.)

Flash point:

143 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Soluble in Acetone, Chloroform, Dichloromethane, Ethanol, Ethyl Acetate and Methanol.

form 

Liquid

Specific Gravity

1.121

color 

Clear colorless to yellow

BRN 

2041344

InChIKey

QMATYTFXDIWACW-UHFFFAOYSA-N

CAS DataBase Reference

445-27-2(CAS DataBase Reference)

NIST Chemistry Reference

o-Fluoroacetophenone(445-27-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39-37

RIDADR 

1993

WGK Germany 

3

HazardClass 

IRRITANT

PackingGroup 

III

HS Code 

29147090

MSDS

• Language:English Provider:1-(2-Fluorophenyl)ethanone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2'-Fluoroacetophenone Usage And Synthesis

Chemical Properties

clear colorless to light yellow or light green

Uses

2'-Fluoroacetophenone is used as starting reagent in the synthesis of ascididemin. It is used to produce 1-(2-piperidin-1-yl-phenyl)-ethanone by reaction with piperidine.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 6179, 1990 DOI: 10.1016/S0040-4039(00)97018-7

General Description

The enantioselective reduction of 2′-fluoroacetophenone has been investigated.

2'-Fluoroacetophenone(445-27-2)Related Product Information

• L-PICEIN
• 2-Fluorophenylacetic acid
• 2',4'-Dichloroacetophenone
• 2-Fluorobenzyl cyanide
• 4'-Hydroxyacetophenone
• 3-Aminoacetophenone
• Acetophenone
• 2-Bromoacetophenone
• 4'-Bromoacetophenone
• 4'-(Trifluoromethyl)acetophenone
• 2'-Hydroxyacetophenone
• 3-Nitroacetophenone
• 4-Nitroacetophenone
• 2-BROMO-2'-FLUOROACETOPHENONE
• ω-Bromo-4-fluoroacetophenone, 4-Fluorophenacyl bromide,2-Bromo-p-fluoroacetophenone,2'-BROMO-4-FLUOROACETOPHENONE,2-BROMO-4'-FLUOROACETOPHENONE
• 2-Fluoropropiophenone
• 2'-Bromoacetophenone
• 5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde