Niraparib tosylate Chemical Properties

solubility 

DMSO: ~64 mg/mL (~199.8 mM)；Ethanol: ~64 mg/mL

form 

Solid

color 

White to off-white

InChIKey

LCPFHXWLJMNKNC-XOIICWPPNA-N

SMILES

S(C1C=CC(C)=CC=1)(O)(=O)=O.C(C1=CC=CC2=CN(C3C=CC([C@H]4CNCCC4)=CC=3)N=C12)(=O)N |&1:23,r|

Niraparib tosylate Usage And Synthesis

FDA Approved

Yes

Uses

Niraparib tosylate hydrate is a sulfonic acid organic compound that can be used as a pharmaceutical intermediate.

Mechanism of action

Niraparib tosylate is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells.

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