N3-PEG6-CH2COOH Chemical Properties

storage temp. 

Storage temp. 2-8°C

form 

Liquid

color 

Colorless to light yellow

N3-PEG6-CH2COOH Usage And Synthesis

Uses

Azido-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N3-PEG6-CH2COOH(880129-82-8)Related Product Information

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• N3-PEG12-CH2CH2COOH
• Azido-PEG1-PFP ester
• Azido-PEG12-NHS ester
• Azido-PEG12-NHS ester
• Azido-PEG5-acid
• Azido-PEG1-acid