4-Aminoguinoline Chemical Properties

Melting point:

151.0 and le 155.0 °C

Boiling point:

312.78°C (estimate)

Density 

1.1148 (estimate)

refractive index 

1.7080 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

powder to crystalline

pka

9.17(at 20℃)

color 

White to Yellow to Orange

CAS DataBase Reference

578-68-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38-36-22-41

Safety Statements 

26-36/37/39-39

RIDADR 

2811

HS Code 

29334900

4-Aminoguinoline Usage And Synthesis

Chemical Properties

Light brown to grey solid

Uses

4-Quinolinamine and its derivatives are commonly used as anti-malarial drugs and also have potential therapeutic effects on patients afflicted with arthritis (and/or related diseases).

Synthesis Reference(s)

Journal of Medicinal Chemistry, 43, p. 4667, 2000 DOI: 10.1021/jm0002073
Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2

Purification Methods

It has been purified by zone refining and recrystallisation from *C6H6, EtOH or H2O. The hydrochloride has m 308o (from MeOH), and the picrate has m 277o (from EtOH). [Albert et al. J Chem Soc 2240 1948, Beilstein 22 III/IV 4611, 22/10 V 341.]

4-Aminoguinoline(578-68-7)Related Product Information

• Quinhydrone
• Ethoxyquin
• 6-Hydroxy-2(1H)-3,4-dihydroquinolinone
• 8-Hydroxyquinoline
• Quinclorac
• Isoquinoline
• QUINOLINE SULPHATE
• Quinoline, 6-hydrazino-, Monohydrochloride
• Quinolin-4-yl-methanol hydrobromide
• 8-HYDRAZINOQUINOLINE
• 3-hydrazinoquinoline dihydrochloride
• Quinolin-5-ylhydrazine hydrochloride
• 4-NITROQUINOLINE N-OXIDE
• 2-Aminoquinoline
• NAM
• 9-HYDRAZINOACRIDINE
• QUINACRINE MUSTARD DIHYDROCHLORIDE
• 5-Aminoquinoline