Pentachloropyridine Chemical Properties

Melting point:

124 °C

Boiling point:

280 °C

Density 

1.7500 (estimate)

vapor density 

8.4 (vs air)

vapor pressure 

0.01 mm Hg ( 20 °C)

storage temp. 

Store below +30°C.

solubility 

9mg/l

form 

Flakes

pka

-6.23±0.50(Predicted)

color 

White to off-white

BRN 

155197

InChIKey

DNDPLEAVNVOOQZ-UHFFFAOYSA-N

CAS DataBase Reference

2176-62-7(CAS DataBase Reference)

NIST Chemistry Reference

Pyridine, pentachloro-(2176-62-7)

EPA Substance Registry System

Pyridine, pentachloro- (2176-62-7)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38-42/43

Safety Statements 

22-26-36-24/25

WGK Germany 

3

RTECS 

UT7000000

TSCA 

Yes

HazardClass 

9

HS Code 

29333999

Hazardous Substances Data

2176-62-7(Hazardous Substances Data)

Toxicity

LD50 ipr-mus: 235 mg/kg TXAPA9 11,361,67

MSDS

• Language:English Provider:2,3,4,5,6-Pentachloropyridine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Pentachloropyridine Usage And Synthesis

Description

Pentachloropyridine is one of the most important perhalogenated compounds which find broad applications in many fields of chemistry. It is most reactive at the 4- position. Reduction with zinc, or electrochemically, yields 2,3,5,6-tetrachloropyridine. Partial hydrolysis and phosphorylation gives the insecticide chlorpyrifos.

Chemical Properties

WHITE TO OFF-WHITE FLAKES

Uses

Pentachloropyridine is a halogenated pyridine with antineoplastic and antiapoptic properties.

Preparation

Pentachloropyridine can be produced through a direct electrophilic substitution reaction between pyridine and chlorine.

Safety Profile

Poison by intraperitoneal route. When heated to decomposition it emits very toxic fumes of Clí and NOx.

Purification Methods

Purify it by recrystallisation from EtOH or aqueous EtOH. It sublimes at 150o/3mm. [den Hertog et al. Recl Trav Chim Pays-Bas 69 673 1950, Schikh et al. Chem Ber 69 2604 1936, Beilstein 20 I 81, 20 III/IV 2503, 20/5 V 422.]

Pentachloropyridine(2176-62-7)Related Product Information

• Clopidol
• 2-Bromo-5-chloropyridine
• 4-Chloropyridinium chloride
• 2-Chloro-5-chloromethylpyridine
• 3-Chloropyridine
• 2,3-Dichloropyridine
• 2,5-Dichloropyridine
• 2,3,5,6-Tetrachloropyridine
• Sulfasalazine
• Chromium picolinate
• 2-Chloro-3-hydroxypyridine
• 2-Amino-5-chloropyridine
• Glutaraldehyde
• Tebuconazole
• 2-Chloropyridine
• pyridinium Chlorochromate
• 2,3,5-Trichloropyridine
• Pyridine hydrochloride