3-Methylbenzoyl chloride Chemical Properties

Melting point:

-23°C

Boiling point:

86 °C/5 mmHg (lit.)

Density 

1.173 g/mL at 25 °C (lit.)

refractive index 

1.5475-1.5495

Flash point:

76 °C

storage temp. 

Inert atmosphere,2-8°C

form 

Liquid

Specific Gravity

1.17

color 

Clear colorless to light brown

Water Solubility 

Reacts with water.

Sensitive 

Moisture Sensitive

BRN 

878419

InChIKey

YHOYYHYBFSYOSQ-UHFFFAOYSA-N

CAS DataBase Reference

1711-06-4(CAS DataBase Reference)

NIST Chemistry Reference

Benzoyl chloride, 3-methyl-(1711-06-4)

EPA Substance Registry System

Benzoyl chloride, 3-methyl- (1711-06-4)

Safety Information

Hazard Codes 

C

Risk Statements 

34-36/37

Safety Statements 

24/25-45-36/37/39-27-26-23

RIDADR 

3265

WGK Germany 

1

RTECS 

DM6644000

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29163990

MSDS

• Language:English Provider:3-Methylbenzoyl chloride
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Methylbenzoyl chloride Usage And Synthesis

Chemical Properties

clear colorless to light brown liquid

Uses

m-Toluoyl chloride has been used to derivatize the C1-C4 aliphatic amines for their determination in air by HPLC. It has been used in determination of atmospheric ammonia by denuder-sampling and HPLC-UV detection.

General Description

m-Toluoyl chloride is an efficient derivatization reagent for amines.

Synthesis

In a 1000 mL three-necked flask equipped with a thermometer, a mechanical stirrer, a reflux condenser tube and an off-gas absorption device, 540.56 g of m-methylbenzoic acid, 573.0 g of thionyl chloride and 1.0 g of N,N-dimethylformamide were added sequentially. The reaction mixture was heated to 90°C and the reaction was continuously stirred at this temperature for 3 hours. Upon completion of the reaction, the system was clear. The excess thionyl chloride was removed by distillation under reduced pressure, and 610.0 g of m-toluoyl chloride was finally obtained, which was determined to have a purity of 98.2% and a yield of 99.3%.

References

[1] Patent: CN107417518, 2017, A. Location in patent: Paragraph 0028
[2] Patent: CN105348085, 2016, A. Location in patent: Paragraph 0026; 0027; 0028; 0029; 0030
[3] Patent: CN107400052, 2017, A. Location in patent: Paragraph 0016
[4] Canadian Journal of Chemistry, 1963, vol. 41, p. 2962 - 2968
[5] Chemische Berichte, 1879, vol. 12, p. 2300

3-Methylbenzoyl chloride(1711-06-4)Related Product Information

• Choline chloride
• Benzoyl chloride
• Thionyl chloride
• Sodium chloride
• 2,4,6-Trimethylbenzoyl chloride
• Ammonium chloride
• 4-Cyanobenzoyl chloride
• Calcium chloride
• 2-(Trifluoromethyl)benzoyl chloride
• 3-(Trifluoromethyl)benzoyl chloride
• 4-Methoxybenzoyl chloride
• 4-Fluorobenzoyl chloride
• alpha,alpha,alpha-Trifluoro-o-toluoyl chloride
• Pivaloyl chloride
• 4-(Chloromethyl)benzoyl chloride
• Polyvinyl chloride
• 4-Chlorobenzoyl chloride
• Potassium chloride