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2-AMINO-3,8-DIMETHYLIMIDAZO[4,5-F]QUINOXALINE

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2-AMINO-3,8-DIMETHYLIMIDAZO[4,5-F]QUINOXALINE Basic information

Product Name:
2-AMINO-3,8-DIMETHYLIMIDAZO[4,5-F]QUINOXALINE
Synonyms:
  • 3H-Imidazo(4,5-F)quinoxalin-2-amine, 3,8-dimethyl-
  • 8-Methyl-iqx
  • Brn 4188271
  • Ccris 2536
  • 2-amino-3,8-dimethyl-3h-imidazo(4,5-f)quinoxaline
  • 5-f)quinoxaline,2-amino-3,8-dimethyl-3h-imidazo(
  • MEIQX
  • 2-AMINO-3,8-DIMETHYLIMIDAZO[4,5-F]QUINOXALINE
CAS:
77500-04-0
MF:
C11H11N5
MW:
213.24
Product Categories:
  • Heterocycles
  • Mutagenesis Research Chemicals
  • Heterocyclic Compounds
Mol File:
77500-04-0.mol
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2-AMINO-3,8-DIMETHYLIMIDAZO[4,5-F]QUINOXALINE Chemical Properties

Melting point:
> 300°C
Boiling point:
343.23°C (rough estimate)
Density 
1.2597 (rough estimate)
refractive index 
1.6880 (estimate)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form 
Solid
pka
2.20±0.50(Predicted)
color 
Yellow to Green
Stability:
Hygroscopic
IARC
2B (Vol. Sup 7, 56) 1993
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Safety Information

Hazard Codes 
T
RTECS 
NJ5925500
Hazard Note 
Toxic
HS Code 
29334900
Hazardous Substances Data
77500-04-0(Hazardous Substances Data)
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2-AMINO-3,8-DIMETHYLIMIDAZO[4,5-F]QUINOXALINE Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

Diet meat mutagen heterocyclic amine colorectal adenoma recurrence.

Uses

Mutagen found in white meat, increasing the rate of colorectal adenomas.

Definition

ChEBI: An imidazoquinoxaline that is 3H-imidazo[4,5-f]quinoxaline substituted at positions 3 and 8 by methyl groups and at position 2 by an amino group. A mutagenic compound found in cooked beef.

Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Carcinogenicity

MeIQx is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and supporting genotoxicity data.

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