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Fmoc-N-methyl-L-leucine

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Fmoc-N-methyl-L-leucine Basic information

Product Name:
Fmoc-N-methyl-L-leucine
Synonyms:
  • N-ALPHA-FMOC-N-ALPHA-METHYL-L-LEUCINE
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-L-LEUCINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-LEUCINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-L-LEUCINE
  • FMOC-L-MELEU-OH
  • FMOC-MELEU-OH
  • FMOC-N-ALPHA-METHYL-L-LEUCINE
  • FMOC-N-ME-LEUCINE
CAS:
103478-62-2
MF:
C22H25NO4
MW:
367.44
Product Categories:
  • Fmoc-Amino acid series
  • Leucine [Leu, L]
  • N-Methyl Amino Acids
  • Amino Acids
Mol File:
103478-62-2.mol
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Fmoc-N-methyl-L-leucine Chemical Properties

Melting point:
113-116 °C
alpha 
-20.5 º (c=1% in DMF)
Boiling point:
537.3±29.0 °C(Predicted)
Density 
1.194±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
3.93±0.21(Predicted)
form 
Powder
color 
White
optical activity
[α]20/D 20.5±0.5°, c = 1% in DMF
Water Solubility 
Slightly soluble in water.
BRN 
3630430
InChI
InChI=1S/C22H25NO4/c1-14(2)12-20(21(24)25)23(3)22(26)27-13-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,14,19-20H,12-13H2,1-3H3,(H,24,25)/t20-/m0/s1
InChIKey
BUJQSIPFDWLNDC-FQEVSTJZSA-N
SMILES
C(O)(=O)[C@H](CC(C)C)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C
CAS DataBase Reference
103478-62-2(CAS DataBase Reference)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29242990

MSDS

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Fmoc-N-methyl-L-leucine Usage And Synthesis

Chemical Properties

White to off-white solid

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

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