Algestone acetophenide
Algestone acetophenide Basic information
- Product Name:
- Algestone acetophenide
- Synonyms:
-
- 16,17-((1-phenylethylidene)bis(oxy))pregn-4-ene-3,20-dione
- 16-alpha,17-alpha-dihydroxyprogesteroneacetophenide
- 16-alpha,17-dihydroxypregn-4-ene-3,20-dionecyclicacetalwithacetophenone
- 17-((1-phenylethylidene)bis(oxy))-20-dion(16-alpha(r))-pregn-4-ene-16
- 20-dione,16-alpha,17-dihydroxy-pregn-4-ene-cyclicacetalwithacetophenone
- 3,5-DIETHYL-1,2 DIHYDRO-1-PHENYL-2-PROPYLPYRIDINE (PDHP)
- alphasoneacetophenide
- bovitrol
- CAS:
- 24356-94-3
- MF:
- C29H36O4
- MW:
- 448.6
- EINECS:
- 246-195-8
- Mol File:
- 24356-94-3.mol
Algestone acetophenide Chemical Properties
- Melting point:
- 150-151°
- alpha
- D23 +51° (CHCl3)
- Boiling point:
- 477.29°C (rough estimate)
- Density
- 1.0455 (rough estimate)
- refractive index
- 1.4800 (estimate)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Sparingly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- CAS DataBase Reference
- 24356-94-3(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xi
MSDS
- Language:English Provider:(16alpha(R))-16,17-((1-Phenylethylidene)bis(oxy))-pregn-4-ene-3,20-dione
Algestone acetophenide Usage And Synthesis
Originator
Neolutin Depo, Medici ,Italy ,1982
Uses
Progestin.
Uses
Algestone Acetophenide is a progestational steroid that has been shown to increase the proteins in milk and serum in goats and decrease the weight gain of kids. Algestone Acetophenide is used as an injectable steroid contraceptive in Chile and Mexico.
Definition
ChEBI: Algestone acetophenide is a 16alpha,17alpha-dihydroxyprogesterone acetophenide. It has a role as an anti-inflammatory drug and a synthetic oral contraceptive.
Manufacturing Process
To a suspension of 500 mg of 16α,17α-dihydroxyprogesterone in 25 ml of freshly redistilled acetophenone is added 0.125 ml of 72% perchloric acid and the mixture is agitated at room temperature for one hour. The clear solution is washed with dilute sodium bicarbonate to remove excess acid and the acetophenone layer, after addition of chloroform is separated from the aqueous phase. The organic layer is dried over sodium sulfate and after removal of the chloroform and acetophenone in high vacuum the residue is crystallized from 95% alcohol. The pure acetophenone derivative has a melting point of about 142°C to 144°C.
brand name
Deladroxone (Bristol-Myers Squibb); Droxone (Bristol-Myers Squibb).
Therapeutic Function
Progestin, Contraceptive
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Algestone acetophenide(24356-94-3)Related Product Information
- 4-Nitroacetophenone
- 2-Bromoacetophenone
- 2'-Hydroxyacetophenone
- Medroxyprogesterone Acetate
- Premarin
- 4'-Methylacetophenone
- 4'-Hydroxyacetophenone
- Progesterone
- 3-Nitroacetophenone
- Algestone
- Chalcone
- Acetophenone
- ACETALDEHYDE DI-N-HEXYL ACETAL
- CIS-1,2-CYCLOPENTANEDIOL
- Alphasone acetonide
- (S)-Glyceraldehyde acetonide
- 2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
- DIPENTOXYETHANE