5-Bromo-2,3-dihydro-1H-inden-1-amine Chemical Properties

Boiling point:

278.2±40.0 °C(Predicted)

Density 

1.490±0.06 g/cm3(Predicted)

storage temp. 

2-8°C(protect from light)

pka

9.05±0.20(Predicted)

InChI

InChI=1S/C9H10BrN/c10-7-2-3-8-6(5-7)1-4-9(8)11/h2-3,5,9H,1,4,11H2

InChIKey

IEUKCNPRRGOGDG-UHFFFAOYSA-N

SMILES

C1(N)C2=C(C=C(Br)C=C2)CC1

5-Bromo-2,3-dihydro-1H-inden-1-amine Usage And Synthesis

Synthesis

To a solution of 5-bromo-2,3-dihydro-1H-inden-1-one (100 g, 474 mmol, 1.00 equiv) in methanol (1.5 L) was added ammonium formate (300 g, 4.76 mol, 10.0 equiv). After stirring for 1 h, NaBH3CN (90 g, 1.43 mol, 3.02 equiv) was added. The mixture was heated at 60 ℃ for 2 h, concentrated under reduced pressure, and purified by silica gel chromatography (EA/PE, 1/10) to afford 64 g (64%) of 5-Bromo-2,3-dihydro-1H-inden-1-amine as a brown solid.

5-Bromo-2,3-dihydro-1H-inden-1-amine(185122-74-1)Related Product Information

• 5-BROMO-2,3-DIHYDRO-BENZOFURAN-3-YLAMINE HYDROCHLORIDE
• 5-bromo-2,4-dimethylphenylamine
• (1R)-1-AMINO-5-BROMOINDANECARBOXYLIC ACID
• 1-(5-bromo-2,3-dihydro-1H-inden-1-yl)hydrazine
• (S)-5-BROMO-2,3-DIHYDRO-1H-INDEN-1-AMINE
• (R)-5-BROMO-2,3-DIHYDRO-1H-INDEN-1-AMINE
• 5-Bromo-2,3-dihydro-1H-inden-1-amine
• (1S)-1-AMINO-5-BROMOINDANECARBOXYLIC ACID