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MORPHINE-D3

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MORPHINE-D3 Basic information

Product Name:
MORPHINE-D3
Synonyms:
  • Morphine-d3 solution
  • Morphine-N-methyl-d3 solution
  • 17-(2H3)Methyl-7,8-didehydro-4,5α-epoxymorphinan-3,6α-diol
  • 7,8-Didehydro-4,5α-epoxy-17-(2H3)methylmorphinan-3,6α-diol
  • 7,8-Didehydro-4,5α-epoxy-17-(2H3)methylmorphinan-3β,6α-diol
  • Brn 0582173
  • Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-trideuteriomethyl-
  • Methanol（test MORPHINE-D3，1.0 mg/mL）
CAS:
67293-88-3
MF:
C17H19NO3
MW:
285.34
EINECS:
621-670-6
Product Categories:
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Pharmaceuticals
  • Chiral Reagents
  • Isotope Labelled Compounds
  • Chiral Reagents, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
67293-88-3.mol
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MORPHINE-D3 Chemical Properties

Melting point:
>2400C (dec,)
Flash point:
11 °C
storage temp. 
−20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
Major Application
forensics and toxicology
InChI
1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1/i1D3
InChIKey
BQJCRHHNABKAKU-LLQNGXJRSA-N
SMILES
O[C@@H](C=C1)[C@H]2C(C1C3C4)(CCN3C([2H])([2H])[2H])C5=C4C=CC(O)=C5O2
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Safety Information

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
36/37-45-16-7
RIDADR 
UN 1230 3/PG 2
WGK Germany 
1
Storage Class
3 - Flammable liquids
Hazard Classifications
Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1
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MORPHINE-D3 Usage And Synthesis

Description

Morphine-d3 (CRM) (Item No. 24514) is an analytical reference standard intended for use as an internal standard for the quantification of morphine (Item Nos. 15464 | ISO60147) by GC- or LC-MS. Morphine is categorized as an opioid. It is a natural phenanthrene commonly used for its analgesic properties but has a high potential for addiction. Morphine is regulated as a Schedule II compound in the United States. Morphine-d3 (CRM) (Item No. 24514) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Chemical Properties

White Solid

Uses

Labelled Morphine (M652290). Principal alkaloid of opium. This is a controlled substance (opiate). Analgesic (narcotic).

Uses

Morphine-d3, is the labeled analogue of Morphine (M652290), the principal alkaloid of opium. This is a controlled substance (opiate). Analgesic (narcotic).

General Description

This stable-labeled internal standard is suitable for quantiation of morphine levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, pain prescription monitoring, clinical toxicology, forensic analysis, or isotope dilution methods. Morphine is a very potent opiate analgesic drug used to relieve both acute and chronic severe pain. Sold under trade names including MS Contin?, Kadian?, Oramorph?, and Roxanol, morphine is also a commonly abused recreational drug due to its widespread availability and high potential for addiction.

References

[1] ANDREA M TRESCOT. Opioid pharmacology.[J]. Pain physician, 2008, 11 2 Suppl: S133-53.

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