AJMZAIPORREFDJ-UHFFFAOYSA-N Chemical Properties

Boiling point:

587.8±50.0 °C(Predicted)

Density 

1.372±0.06 g/cm3(Predicted)

pka

4.54±0.10(Predicted)

AJMZAIPORREFDJ-UHFFFAOYSA-N Usage And Synthesis

Uses

A Tolvaptan (T536650) Impurity.

Definition

ChEBI: DM-4107 is a 4-hydroxy monocarboxylic acid that is 4-hydroxybutanoic acid substituted at position 4 with a 5-chloro-2-[2-methyl-4-(2-methylbenzamido)benzamido]phenyl group. An hydroxybutyric acid metabolite of the vasopressin V2-receptor antagonist tolvaptan. It has a role as a drug metabolite. It is a 4-hydroxy monocarboxylic acid and a benzenedicarboxamide. It is functionally related to a tolvaptan.

AJMZAIPORREFDJ-UHFFFAOYSA-N(1346599-75-4)Related Product Information

• Benzamide, N-[4-[[(4S,5S)-7-chloro-2,3,4,5-tetrahydro-4,5-dihydroxy-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl-
• (R)-(+)-Tolvaptan
• Benzoic acid, 2-methyl-4-[(2-methylbenzoyl)[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]amino]-
• Rac-Trans-4-Hydroxy Tolvaptan
• 5-Chloro-2-[[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester
• Benzamide, N-[4-[(7-chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methyl-4-[(2-methylbenzoyl)amino]-
• N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide
• Tolvaptan Impurity 3 (DM-4104)
• Tolvaptan Impurity 65
• (S)-(-)-Tolvaptan
• Tolvaptan Impurity 11
• N-[4-[[7-Chloro-2,3,4,5-tetrahydro-5-(phosphonooxy)-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methylbenzamide
• Tolvaptan Impurity 4 (DM-4105)
• Tolvaptan Impurity 7
• 3-Chloro-2-methylbenzoyl chloride
• Tolvaptan Impurity 25
• N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methyl-N-(2-methylbenzoyl)-4-[(2-methylbenzoyl)amino]benzamide
• 5-chloro-2-methylbenzoyl chloride