Phenyl trifluoromethanesulfonate Chemical Properties

Boiling point:

99-100 °C/60 mmHg (lit.)

Density 

1.396 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.435(lit.)

Flash point:

160 °F

storage temp. 

Inert atmosphere,Room Temperature

form 

clear liquid

color 

Colorless to Almost colorless

Safety Information

Hazard Codes 

T

Risk Statements 

36/37/38-34-24/25

Safety Statements 

26-36-45-36/37/39

RIDADR 

UN 2927 6.1/PG 2

WGK Germany 

3

HS Code 

29049090

MSDS

• Language:English Provider:SigmaAldrich

Phenyl trifluoromethanesulfonate Usage And Synthesis

Chemical Properties

Colorless Liquid.

Uses

Phenyl trifluoromethanesulfonate (phenyl triflate) may be used in the following studies:
As an arylating agent for the asymmetric α-arylation of ketones catalyzed by Pd(dba)2 and difluorphos.
As a reactant in the one pot synthesis of carbazoles by palladium-catalyzed N-arylation of anilines with phenyl triflate followed by oxidative coupling.
Synthesis of N-(2,6-diarylbenzoyl)anilines by diarylation of benzanilides with phenyl triflate in the presence of palladium-based catalyst.
As an arylating agent in the synthesis of (R)-2-phenyl-2,3-dihydrofuran by the arylation of 2,3-dihydrofuran.

Preparation

Synthesis of Phenyl trifluoromethanesulfonate: The reaction of phenol (1.00 g, 10.6 mmol) with triflic anhydride as outlined in the general procedure provided phenyl trifluoromethanesulfonate as colorless oil (0.73 g, 30%).
1H NMR (400 MHz, CDCl3) δ 7.50 – 7.42 (m, 2H), 7.41 – 7.36 (m, 1H), 7.32 – 7.24 (m, 2H).

General Description

Phenyl trifluoromethanesulfonate (phenyl triflate) is an aryl fluorosulphonate. It has been synthesized by the reaction of phenol with fluorosulphonic anhydride.

Phenyl trifluoromethanesulfonate(17763-67-6)Related Product Information

• 4-BROMOPHENYL TRIFLUOROMETHANESULFONATE
• Trimethylsilyl trifluoromethanesulfonate
• TRIFLUOROMETHYL SULFINYL CHLORIDE
• SILVER TRIFLUOROMETHANESULFONATE
• Trifluoromethanesulfonyl chloride
• Ethyl trifluoromethanesulfonate
• Trifluoromethanesulfonic anhydride
• Sodium trifluoromethanesulfonate
• Trifluoromethanesulfonic acid
• Lithium trifluoromethanesulfonate
• Methyl trifluoromethanesulfonate
• 4-METHYL-2-(TRIMETHYLSILYL)PHENYL TRIFLUOROMETHANESULFONATE,98.0+%(GC),4-METHYL-2-(TRIMETHYLSILYL)PHENYL TRIFLUOROMETHANESULFONATE
• P-TOLYL TRIFLATE
• 1-NAPHTHYL TRIFLATE
• 4-NITROPHENYL TRIFLUOROMETHANESULFONATE
• 2-(TRIMETHYLSILYL)PHENYL TRIFLUOROMETHANESULFONATE
• METHYL 2-TRIFLUOROMETHANESULFONYLOXY-1-NAPHTHOATE
• (R)-(-)-1,1'-Binaphthol-2,2'-bis(trifluoromethanesulfonate)