1-Bromo-2-nitrobenzene Chemical Properties

Melting point:

40-42 °C (lit.)

Boiling point:

261 °C (lit.)

Density 

1.7 g/cm3 (20℃)

refractive index 

1.6060 (estimate)

Flash point:

>230 °F

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

powder to crystal

color 

Light yellow to Amber to Dark green

Water Solubility 

insoluble

BRN 

2044109

Stability:

Stable. Combustible. Incompatible with strong bases, strong oxidizing agents.

CAS DataBase Reference

577-19-5(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1-bromo-2-nitro-(577-19-5)

EPA Substance Registry System

o-Bromonitrobenzene (577-19-5)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38-22

Safety Statements 

36/37-36/37/39-26-22

RIDADR 

UN 3459 6.1/PG 3

WGK Germany 

3

RTECS 

CY9040450

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29049085

MSDS

• Language:English Provider:1-Bromo-2-nitrobenzene
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1-Bromo-2-nitrobenzene Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

1-Bromo-2-nitrobenzene is used in organic synthesis. It also can react with 2-methylamino-benzoic acid to get N-methyl-N-(2-nitro-phenyl)-anthranilic acid. And it is also used in the preparation of 4-methoxy-2?-nitrodiphenyl ether, 1-methoxy-3,5-bis-(2-nitro-phenoxy)benzene.

Uses

1-Bromo-2-nitrobenzene may be used in the preparation of:

• 4-methoxy-2′-nitrodiphenyl ether
• 1-methoxy-3,5-bis-(2-nitro-phenoxy)benzene
• 5-hydroxy-3-methoxy-2′-nitrodiphenyl ether

General Description

1-Bromo-2-nitrobenzene undergoes palladium[0]-mediated Ullmann cross-coupling reaction with a range of β-halo-enals, -enones or -esters to afford the corresponding β-aryl derivatives. Palladium[0]-mediated Ullmann cross-coupling reaction of 1-bromo-2-nitrobenzene with β-bromo-α,β-unsaturated aldehydes is reported.

Purification Methods

Crystallise it twice from pet ether, using charcoal before the first crystallisation. [Beilstein 5 III 618, 5 IV 728.]

1-Bromo-2-nitrobenzene(577-19-5)Related Product Information

• 4-Bromophenethyl alcohol
• 3-Bromoanisole
• 4'-Bromopropiophenone
• 2-Bromofluorobenzene
• 1-Chloro-3-nitrobenzene
• 4-Bromobenzaldehyde
• Sodium 3-nitrobenzenesulphonate
• 4-Nitrobenzoic acid
• Bromoxynil
• Bromoxynil octanoate
• Bromine
• 1-Bromo-3-nitrobenzene,99%,1-BROMO-3-NITROBENZENE,3-Bromo-1-nitrobenzen
• 1,3-Dinitrobenzene
• 1-BROMO-4-(METHYLSULPHONYL)-2-NITROBENZENE
• 1-Bromo-2-nitrobenzene
• 4'-BROMO-3'-NITROACETOPHENONE
• 4-BROMO-3-NITROANISOLE
• 2,5-Dibromonitrobenzene