PYR-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-D-PHE-LEU-MET-NH2 Chemical Properties

Density 

1.46±0.1 g/cm3(Predicted)

storage temp. 

-15°C

pka

13.04±0.46(Predicted)

form 

Solid

Water Solubility 

Soluble to 1 mg/ml in water

Sequence

{Pyr}-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-{d-Phe}-Leu-Met-NH2

PYR-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-D-PHE-LEU-MET-NH2 Usage And Synthesis

Uses

[D-Phe12]-Bombesin is a derivative of Bombesin (HY-P0195) and an antagonist for bombesin receptor with Ki of 4.7 μM. [D-Phe12]-Bombesin inhibits the Bombesin (HY-P0195)-induced amylase release, with IC50 of 4 μM[1].

References

[1] Heinz-Erian P, et al., [D-Phe12]bombesin analogues: a new class of bombesin receptor antagonists. Am J Physiol. 1987 Mar;252(3 Pt 1):G439-42. DOI:10.1152/ajpgi.1987.252.3.G439

PYR-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-D-PHE-LEU-MET-NH2(108437-87-2)Related Product Information

• L-Pyroglutamamide
• AC-TRP-NHME
• L-TRP-GLY AMIDE
• AC-TRP-NH2
• (2R)-3-PHENYL-1,2-PROPANEDIAMINE
• AC-MET-NH2
• Butanamide, N-(4-amino-4-oxobutyl)-
• PYR-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-D-PHE-LEU-MET-NH2
• 5-AMINOMETHYL-PYRROLIDIN-2-ONE
• H-D-PHE-NH2
• GLY-LEU-MET-NH2
• (S)-5-AMINOMETHYL-PYRROLIDIN-2-ONE
• 5-OXOPYRROLIDINE-2-CARBOXAMIDE