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1-Phenethyl-4-piperidone

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1-Phenethyl-4-piperidone Basic information

Product Name:
1-Phenethyl-4-piperidone
Synonyms:
  • 1-(2-phenylethyl)-4-piperidinon
  • 4-Piperidone, 1-phenethyl-
  • 1-(beta-Phenethyl)-4-piperidone,98%
  • 1-(beta-Phenethyl)-4-piperidone, 98% 5GR
  • 4-(4-Hydroxy-3-Methoxyphenyl)-5-(3-Methoxypropyl)-3-(thiophen-2-yl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one
  • 1-(2-Phenethyl)-4-piperidinone Hydrochloride
  • 4-Piperidinone, 1-(2-phenylethyl)-
  • N-Phenylethyl-4-piperidone
CAS:
39742-60-4
MF:
C13H17NO
MW:
203.28
EINECS:
254-613-5
Product Categories:
  • Aromatics
  • Heterocycles
  • Piperidones
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Piperidine
  • API intermediates
  • Benzenes
  • Building Blocks
  • Heterocyclic Building Blocks
  • research chemical
  • pharmaceutical intermediates
Mol File:
39742-60-4.mol
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1-Phenethyl-4-piperidone Chemical Properties

Melting point:
57-60 °C(lit.)
Boiling point:
341.6°C (rough estimate)
Density 
1.0156 (rough estimate)
refractive index 
1.5400 (estimate)
storage temp. 
Store below +30°C.
solubility 
ethanol: soluble, clear to hazy, light yellow to yellow (50 mg/mL)
pka
8.02±0.20(Predicted)
form 
A crystalline solid
BRN 
130302
InChIKey
YDJXNYNKKXZBMP-UHFFFAOYSA-N
CAS DataBase Reference
39742-60-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,C,F
Risk Statements 
22-34-11
Safety Statements 
22-24/25-45-26-36/37/39-16
RIDADR 
2811
WGK Germany 
3
RTECS 
TN8990300
10
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29333999

MSDS

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1-Phenethyl-4-piperidone Usage And Synthesis

Description

1-phenethyl-4-piperidone is a derivative of 4-piperidinone, being used as an intermediate during the manufacture of chemicals. It is applied for the manufacturing of phenethyl derivative of the propanamide as well as the synthesis of l-Phenethylazacycloheptan-4 -one. It is also used in drugs such as illicitly manufactured nonpharmaceutical fentanyl (NPF) (a potent agonist of opioidreceptors used for anaesthesia and analgesia.

Chemical Properties

YELLOW-BROWN CRYSTALLINE POWDER

Uses

An intermediate of Fentanyl (F275000) and Fenspiride (F265000).

Uses

1-Phenethyl-4-piperidone was used in the preparation of phenethyl derivative of the propanamide. It was also used to synthesize l-Phenethylazacycloheptan-4-one.

References

https://en.wikipedia.org/wiki/N-Phenethyl-4-piperidinone
Jones, T. S, et al. "Nonpharmaceutical Fentanyl-Related Deaths — Multiple States, April 2005–March 2007." Morbidity & Mortality Weekly Report 57.29(2008): 793-796.
https://www.alfa.com/en/catalog/B21146/

1-Phenethyl-4-piperidone Preparation Products And Raw materials

Raw materials

1-Phenethyl-4-piperidoneSupplier