(R)-(-)-Phenylsuccinic acid Chemical Properties

Melting point:

173-176 °C

alpha 

-175 º (c=1%, acetone)

Boiling point:

290.62°C (rough estimate)

Density 

1.2534 (rough estimate)

refractive index 

1.5430 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Acetone (Slightly), Methanol (Slightly)

pka

3.60±0.10(Predicted)

form 

Solid

color 

White to Off-White

optical activity

[α]20/D 175±4°, c = 1% in acetone

BRN 

3201702

CAS DataBase Reference

46292-93-7(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

2917399590

MSDS

• Language:English Provider:SigmaAldrich

(R)-(-)-Phenylsuccinic acid Usage And Synthesis

Chemical Properties

almost white fine powder

Uses

(R)-Phenylsuccinic Acid is an intermediate used in the preparation of optically active succinic acid derivatives used as hypoglycemic agents.

Definition

ChEBI: 2-Phenylsuccinic acid is a member of benzenes and a monocarboxylic acid.

Purification Methods

Purify the acids by re-precipitation from alkali and recrystallisation from H2O. [Naps & Johns J Am Chem Soc 62 2450 1940, Fredga & Matell Bull Soc Chim Belg 62 47 1953, Wren & Williams J Chem Soc 109 572 1916.] The racemate [635-51-8] has m 166-168o, 168o after recrystallisation from H2O or MeCN. Its S-benzylisothiuronium salt has m 164-165o (from EtOH) [Griediger & Pedersen Acta Chem Scand 9 1425 1955]. [Beilstein 9 IV 3351.]

(R)-(-)-Phenylsuccinic acid(46292-93-7)Related Product Information

• Metroprolol succinate
• Disodium succinate
• DL-Phenylsuccinic acid
• DODECENYLSUCCINIC ACID
• Succinic acid
• SULFOSUCCINIC ACID
• Citric acid
• iron succinate
• meso-2,3-Dibromosuccinic acid
• Succimer
• Hyaluronic acid
• Folic acid
• Diethyl succinosuccinate
• Ethyl 2-(Chlorosulfonyl)acetate
• Ascoric Acid
• (S)-(+)-Phenylsuccinic acid, 99+%,(S)-(+)-PHENYLSUCCINIC ACID
• N-(4-CARBOXYPHENYL)SUCCINAMIC ACID
• (R)-(+)-2-BENZYLSUCCINIC ACID 1-METHYL ESTER