MICRONOMICIN SULFATE
MICRONOMICIN SULFATE Basic information
- Product Name:
- MICRONOMICIN SULFATE
- Synonyms:
-
- 6'-N-METHYLGENTAMICIN C1A HEMIPENTASULFATE
- MICRONOMICIN SULFATE
- MICRONOMYCIN SULFATE
- Micronomicin sulfate JAS1998
- D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-a-D-erythro-hexopyranosyl-(14)-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(16)]-2-deoxy-, sulfate (salt) (9CI)
- streptamine,o-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-d-erythro-hexop
- sulfate,d-1-6))-2-deoxy
- yranosyl-(1-4)-o-(3-deoxy-4-c-methyl-3-(methylamino)-beta-l-arabinopyranosyl-(
- CAS:
- 66803-19-8
- MF:
- C20H43N5O11S
- MW:
- 561.65
- EINECS:
- 1308068-626-2
- Mol File:
- 66803-19-8.mol
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MICRONOMICIN SULFATE Chemical Properties
- Melting point:
- >205°C (dec.)
- Boiling point:
- 667℃
- RTECS
- WK2196000
- Flash point:
- >110°(230°F)
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- DMSO (Very Slightly, Heated, Sonicated), Water (Slightly)
- form
- Solid
- color
- White to Pale Yellow
- Water Solubility
- Freely soluble in water
- Stability:
- Hygroscopic
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MICRONOMICIN SULFATE Usage And Synthesis
Uses
Micronomicin Sulfate is an aminoglycoside antibiotic with neuromuscular blocking activity.
Definition
ChEBI: Micronomicin sulfate is an aminoglycoside sulfate salt. It is functionally related to a micronomicin.
in vivo
Micronomicin sulfate is highly active against various bacterial infections in mice, and has an intravenous acute LD50 in mice of 93 mg/kg[1].Micronomicin sulfate (intravenous injection; 4-100 mg/kg; 30 days) is injected for subacute toxicity study. The wistar rats dies at the dose level of 100 mg/kg (10 out of 30 animals): renal disorders and ataxia. The renal histological disorders occurrs mainly at the dose levels of 25 mg/kg and over[3].
| Animal Model: | Wistar rats[3] |
| Dosage: | 4, 10, 25, 63 mg/kg and 100 mg/kg |
| Administration: | Intravenous injection; 30 days |
| Result: | Led to death of rat at 100 mg/kg. |
IC 50
Aminoglycoside
MICRONOMICIN SULFATESupplier
Hunan Hui Bai Shi Biotechnology Co., Ltd.
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- 0731-85526065 13308475853
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Guangzhou Isun Pharmaceutical Co., Ltd
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Shanghai Macklin Biochemical Co.,Ltd.
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- 15221275939
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Shanghai EFE Biological Technology Co., Ltd.
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- 021-65675885 18964387627
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Shanghai QianYan Bio-technology Co., Ltd
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- 02781293128
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