Trimebutine maleate Chemical Properties

Melting point:

122-124°C

storage temp. 

2-8°C

solubility 

Slightly soluble in water, soluble in acetonitrile, sparingly soluble in acetone, slightly soluble in ethanol (96 per cent).

color 

White

InChIKey

FSRLGULMGJGKGI-BTJKTKAUSA-N

CAS DataBase Reference

34140-59-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-27-36/37/39-45

WGK Germany 

2

RTECS 

DI0360000

MSDS

• Language:English Provider:SigmaAldrich

Trimebutine maleate Usage And Synthesis

Chemical Properties

White Solid

Uses

Trimebutine maleate is an antispasmodic that functions as an opioid receptor agonist. Its mechanism of action involves regulating bowel movements and enhancing gastrointestinal function. Trimebutine is commonly used in the treatment of Irritable bowel syndrome. It is also used to restart the movement of the gut after abdominal surgery and to prevent intestinal blockage (paralytic ileus).

Definition

ChEBI: Trimebutine maleate is a trihydroxybenzoic acid that is proposed as a spasmolytic with possible local anesthetic action for the treatment of gastrointestinal disorders.

Side effects

Possible side effects of trimebutine may include dry mouth, heartburn, nausea, diarrhea, constipation, drowsiness, dizziness, tiredness, indigestion, or headache. Other less frequent side effects are difficulty urinating, hearing loss, or painful breast enlargement. If any of these symptoms persist or worsen, please inform your doctor or pharmacist immediately.

References

https://www.drugs.com/medical-answers/trimebutine-3571789/
Trimebutine: abuse, addiction and overdose
https://myhealth.alberta.ca/Health/medications/Pages/conditions.aspx?hwid=fdb8090

Trimebutine maleate(34140-59-5)Related Product Information

• Trimebutine
• Methyl 3,4,5-trimethoxybenzoate
• 1-Dimethylamino-2-phenylbutan-2-yl 3,4,5-trimethoxybenzoate
• DESMETHYL TRIMEBUTINE HCL
• ETHYL 3,5-DIMETHOXYBENZOATE
• Methyl 4,5-dimethoxy-3-hydroxybenzoate
• 2-DIMETHYLAMINO-2-METHYL-1-PROPANOL
• Methyl syringate
• 3,5-Dimethoxybenzoic acid
• Vanillyl butyl ether
• Trimebutine maleate
• 3-Hydroxy-4,5-dimethoxybenzoic acid
• 3,4,5-Trimethoxy benzoic acid
• Ethyl 3,4,5-trimethoxybenzoate
• 2-Phenylpropyl acetate
• fedotozine
• METHYL-BETA-D-GALACTOPYRANOSIDE
• Syringic acid