2-Chloro-5-nitrobenzonitrile Chemical Properties

Melting point:

105-107 °C (lit.)

Boiling point:

122 °C / 0.6mmHg

Density 

1.6133 (rough estimate)

refractive index 

1.5557 (estimate)

storage temp. 

Sealed in dry,Room Temperature

form 

powder to crystal

color 

White to Orange to Green

BRN 

1818642

InChIKey

ZGILLTVEEBNDOB-UHFFFAOYSA-N

CAS DataBase Reference

16588-02-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-37/39-36

RIDADR 

3276

WGK Germany 

3

RTECS 

DI3040000

HazardClass 

IRRITANT

HS Code 

29269090

MSDS

• Language:English Provider:2-Chloro-5-nitrobenzonitrile
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Chloro-5-nitrobenzonitrile Usage And Synthesis

Chemical Properties

LIGHT YELLOW CRYSTALLINE POWDER. 2-Chloro-5-nitrobenzonitrile [16588-02-6], 1-chloro-2-cyano-4-nitrobenzene, Mr 182.57, mp 108 – 109℃, forms yellow needle-shaped crystals. The chlorine atom ortho to the nitrile group is prone to a range of nucleophilic substitution reactions, of which that with ammonia has achieved industrial importance. The nitrile is produced by nitration of 2-chlorobenzonitrile (see above) at 0 ℃.

Uses

2-Chloro-5-nitrobenzonitrile was used in online detection of rat glutathione S-transferase P1-specific inhibitors by high-resolution screening technology.

General Description

2-Chloro-5-nitrobenzonitrile effectively conjugates with rat glutathione S-transferase (GST) isoenzymes and is an alternative model substrate in GST-research.

2-Chloro-5-nitrobenzonitrile(16588-02-6)Related Product Information

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