8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one
8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one Basic information
- Product Name:
- 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one
- Synonyms:
-
- Palbociclib-021
- Palbociclib-3
- Palbociclib impurity 22/8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl) amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one
- Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-cyclopentyl-6-ethenyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-
- 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride
- Palbociclib EP Impurity-G
- Palbociclib Impurity 77 0.7HCl 0.3HCOOH
- CAS:
- 2204863-06-7
- MF:
- C24H29N7O
- MW:
- 431.53
- Mol File:
- 2204863-06-7.mol
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8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one Chemical Properties
- Boiling point:
- 672.3±65.0 °C(Predicted)
- Density
- 1.306±0.06 g/cm3(Predicted)
- solubility
- DMSO (Very Slightly, Heated)
- form
- Solid
- pka
- 8.66±0.10(Predicted)
- color
- Light Yellow
- InChI
- InChI=1S/C24H29N7O/c1-3-19-16(2)20-15-27-24(29-22(20)31(23(19)32)17-6-4-5-7-17)28-21-9-8-18(14-26-21)30-12-10-25-11-13-30/h3,8-9,14-15,17,25H,1,4-7,10-13H2,2H3,(H,26,27,28,29)
- InChIKey
- BAMRZESJXFABIT-UHFFFAOYSA-N
- SMILES
- C1(NC2=NC=C(N3CCNCC3)C=C2)=NC=C2C(C)=C(C=C)C(=O)N(C3CCCC3)C2=N1
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8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one Usage And Synthesis
Uses
Desoxo-palbociclib is a derivative compound of Palbociclib (P139900). Palbociclib (also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-oneSupplier
Scinova Biotech(Guangzhou) Co., Ltd. Gold
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- 13268215580
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Arizest(Shanghai)Pharmatech Co.,Ltd Gold
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- 60753300-53010 13671599112
- geshi.zhuang@acebright.com
Daicel Chiral Technologies (China)CO.,LTD
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- 021-50460086-9 15921403865
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Beijing Comparison Pharmaceutical Technology Co., Ltd
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- 010-52878169 15701683040
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ChemStrong Scientific Co.,Ltd
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- 0755-0755-66853366 13670046396
- sales@chem-strong.com
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8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one(2204863-06-7)Related Product Information
- Palbociclib Impurity 20
- PalBociclib Impurity 22
- 4-(3-NITRO-PYRIDIN-2-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- Palbociclib-007
- tert-Butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate
- Palbociclib
- 4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- Palbociclib-029
- Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-
- Phosphine oxide, tris (2-methylphenyl)-
- Palbociclib-030
- tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
- 1-Piperazinecarboxylic acid, 4-(2-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester
- 5-(piperazin-1-yl)pyridin-2-aMine
- Palbociclib-012
- 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
- PD 0332991 HCl
- 5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine