3-Amino-5-methylisoxazole Chemical Properties

Melting point:

59-61 °C(lit.)

Boiling point:

183.6°C (rough estimate)

Density 

1.1890 (rough estimate)

refractive index 

1.4327 (estimate)

storage temp. 

2-8°C

solubility 

soluble

pka

2.40±0.10(Predicted)

form 

Solid

color 

Off-White to Brown

PH

6.0-7.5 (10g/l, H2O, 20℃)

Water Solubility 

soluble

BRN 

108110

InChIKey

FKPXGNGUVSHWQQ-UHFFFAOYSA-N

CAS DataBase Reference

1072-67-9(CAS DataBase Reference)

NIST Chemistry Reference

3-Isoxazolamine, 5-methyl-(1072-67-9)

EPA Substance Registry System

3-Isoxazolamine, 5-methyl- (1072-67-9)

Safety Information

Hazard Codes 

Xi-F,Xi,F,Xn

Risk Statements 

5-36/37/38-11-36/37/38/5-20/21/22

Safety Statements 

22-24/25-47-37/39-26-16-26/37/39/47-36

WGK Germany 

3

F 

4.6

Hazard Note 

Irritant

HS Code 

29349990

MSDS

• Language:English Provider:5-Methylisoxazol-3-amine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Amino-5-methylisoxazole Usage And Synthesis

Chemical Properties

yellow crystalline powder, crystals and chunks

Uses

3-Amino-5-methylisoxazole was used in synthesis of:

• naphtho[1,2-e][1,3]oxazines
• series of 1-aryl-4-methyl-3,6-bis-(5-methylisoxazol-3-yl)-2-thioxo-2,3,6,10b-tetrahydro-1H-pyrimido[5,4-c]quinolin-5-ones, having potential mosquito larvicidal activity
• hydroxylamines of sulfadiazine and sulfamethoxazole

Uses

Sulfamethoxazole (SMX) (S699086) Impurity. A degradation product in water by a bioluminescence method during application of the electro-Fenton treatment.

General Description

3-Amino-5-methylisoxazole is the major intermediate formed during sulfamethoxazole biodegradation by Pseudomonas psychrophila strain HA-4. It is the intermediate formed during the photocatalytic degradation of sulfamethoxazole (SMX).

3-Amino-5-methylisoxazole(1072-67-9)Related Product Information

• Dibenzylamine
• 1-CHLOROMETHYL-1H-1,2,4-TRIAZOLE
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• ALTRENOGEST
• 2-Aminophenol
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• Bis(2-ethylhexyl)amine
• Tris(hydroxymethyl)aminomethane
• Triethylamine
• N,N-Dimethyl-1,4-phenylenediamine
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• ISOXICAM
• 3-AMINO-4-BROMO-5-METHYLISOXAZOLE
• 3-Amino-5-tert-butylisoxazole