ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > Metabolism > PDE inhibitors > S- (+)-Rolipram
S- (+)-Rolipram
S- (+)-Rolipram Basic information
- Product Name:
- S- (+)-Rolipram
- Synonyms:
-
- (S)-(+)-ROLIPRAM
- (4S)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one
- Rolipram (S)-(+)-
- (4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one
- (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
- (+)-ROLIPRAM;(S)-ROLIPRAM
- (4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone
- (S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
- CAS:
- 85416-73-5
- MF:
- C16H21NO3
- MW:
- 275.34
- Product Categories:
-
- Signalling
- Cyclic Nucleotide related
- Inhibitors
- Mol File:
- 85416-73-5.mol
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S- (+)-Rolipram Chemical Properties
- Melting point:
- 133-136℃
- Density
- 1.155
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO : 100 mg/mL (363.19 mM; Need ultrasonic)
- form
- White to off-white solid.
- color
- White to Almost white
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S- (+)-Rolipram Usage And Synthesis
Uses
S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer
Uses
S-(+)-Rolipram is an inhibitor of cyclic AMP-specific phosphodiesterase. It is the S isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor
Definition
ChEBI: The (S)-enantiomer of rolipram.
Biological Activity
Less active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ).
storage
Room temperature
S- (+)-RolipramSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
TCI (Shanghai) Development Co., Ltd.
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
Ascent Scientific
- Tel
- 4401179829988
- customerservice@ascentscientific.co.uk
Hunan Hui Bai Shi Biotechnology Co., Ltd.
- Tel
- 0731-85526065 13308475853
- ivy@hnhbsj.com
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S- (+)-Rolipram(85416-73-5)Related Product Information
- ZARDAVERINE
- RO 20-1724
- Roflumilast
- 4-(3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL)PYRROLIDIN-2-ONE
- ETAZOLATE
- BRL 50481
- Vinpocetine
- ZAPRINAST
- Cilostazol
- CILOSTAMIDE
- AG 1295
- (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
- 4-[[3,4-(METHYLENEDIOXY)BENZYL]AMINO]-6-CHLOROQUINAZOLINE
- EHNA HYDROCHLORIDE
- S- (+)-Rolipram
- 4-(3'-Methoxyphenyl)-2-pyrrolidinone
- 4-(4'-Methoxyphenyl)-2-pyrrolidinone
- 1-(4-bromobenzyl)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one