1-Phenyl-2-pyrrolidinone Chemical Properties

Melting point:

67-69 °C (lit.)

Boiling point:

123 °C/0.2 mmHg (lit.)

Density 

1.0840 (rough estimate)

refractive index 

1.5200 (estimate)

Flash point:

123°C/0.2mm

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Ethyl Acetate, Methanol (Slightly)

form 

Solid

pka

0.54±0.20(Predicted)

color 

Light Beige

Water Solubility 

Soluble in chloroform and ethyl Acetate. Insoluble in water.

BRN 

130685

CAS DataBase Reference

4641-57-0(CAS DataBase Reference)

NIST Chemistry Reference

2-Pyrrolidinone, 1-phenyl-(4641-57-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29337900

MSDS

• Language:English Provider:SigmaAldrich

1-Phenyl-2-pyrrolidinone Usage And Synthesis

Chemical Properties

Light Beige Solid

Uses

A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity.

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 4079, 1955 DOI: 10.1021/ja01620a034
Synthesis, p. 856, 1985

1-Phenyl-2-pyrrolidinone(4641-57-0)Related Product Information

• 2-Pyrrolidinone
• Polyvinylpyrrolidone
• N-Methyl-2-pyrrolidone
• N-Methyl-2-pyrrolidone
• PHENYL VALERATE
• Povidone iodine
• N-Vinyl-2-pyrrolidone
• PHENYL RESIN
• Phenylacetic acid
• METHYL-2-PYRROLIDONE
• Procymidone
• N-PHENYLSUCCINIMIDE
• 1-(4-FLUOROPHENYL)-2-PYRROLIDINONE
• 4-Phenyl-2-Pyrrolidinone-1-Acetamide
• 3-chloro-4-(chloromethyl)-1-(3-(trifluoromethyl)phenyl)-2-pyrrolidinon
• 3-METHOXYCARBONYL-4-PHENYL-2-PYRROLIDINONE
• Doxapram
• 1-(4-BROMOPHENYL)-2-PYRROLIDINONE