ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Proline derivatives > Boc-Hyp-OH
Boc-Hyp-OH
Boc-Hyp-OH Basic information
- Product Name:
- Boc-Hyp-OH
- Synonyms:
-
- (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
- (2S,4R)-N-t-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic Acid
- Boc-(2S,4R)-4-Hydroxy-2-pyrrolidinecarboxylic Acid
- N-ter
- N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline ,98%
- Boc-L-trans-hydroxyproline(Boc-trans-Hyp-OH) ,98.5%(HPLC)
- 1,2-Pyrrolidinedicarboxylicacid,4-hydroxy-,1-(1,1-diMethylethyl)ester,(2S,4R)-
- (2S)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
- CAS:
- 13726-69-7
- MF:
- C10H17NO5
- MW:
- 231.25
- EINECS:
- 604-011-7
- Product Categories:
-
- Hydroxyproline [Hyp]
- Unusual Amino Acids
- AMINOACIDS DERIVATIVES
- Pyrrole&Pyrrolidine&Pyrroline
- Amino Acids
- Amino Acids (N-Protected)
- Biochemistry
- Boc-Amino Acids
- Boc-Amino acid series
- 1
- bc0001
- Mol File:
- 13726-69-7.mol
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Boc-Hyp-OH Chemical Properties
- Melting point:
- 123-127 °C(lit.)
- alpha
- -78 º (in H2O)
- Boiling point:
- 390.9±42.0 °C(Predicted)
- Density
- 1.312±0.06 g/cm3(Predicted)
- refractive index
- -68 ° (C=1, MeOH)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 3.80±0.40(Predicted)
- form
- Powder
- color
- White to off-white
- optical activity
- [α]20/D 53.5±2°, c = 1% in DMF
- Water Solubility
- very faint turbidity
- BRN
- 4295484
- InChIKey
- BENKAPCDIOILGV-RQJHMYQMSA-N
- CAS DataBase Reference
- 13726-69-7(CAS DataBase Reference)
- EPA Substance Registry System
- (2S,4R)-1-tert-Butyl 4-hydroxy-1,2-pyrrolidinecarboxylate (13726-69-7)
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 2933 99 80
- HazardClass
- IRRITANT
MSDS
- Language:English Provider:SigmaAldrich
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Boc-Hyp-OH Usage And Synthesis
Chemical Properties
White powder
Uses
Boc-Hyp-OH is used in the preparation of hydroxyproline derivatives. It is an intermediate in the synthesis of Fosinopril-d5 Sodium Salt (F727803), the labeled analogue of Fosinopril Sodium Salt (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
Biological Activity
Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Boc-Hyp-OHSupplier
future industrial shanghai co., ltd Gold
- Tel
- 400-0066400 13621662912
- sales@jonln.com
Shanghai Jizhi Biochemical Technology Co. Ltd. Gold
- Tel
- 400-400-400-9004166 18616739031
- 3007523370@qq.com
BTC Pharmaceutical CO. Ltd Gold
- Tel
- 0513-0513-68015-397-397 15716293042
- sales14@btcpharm.com
GenChem & GenPharm (Changzhou) Co., Ltd. Gold
- Tel
- 0519-85720003 18861157602
- sales03@genchem.cn
Shanghai Hobor Chemical Co., Ltd Gold
- Tel
- 21-21-61026752 13918007836
- sales@hoborchem.com
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Boc-Hyp-OH(13726-69-7)Related Product Information
- L-Hydroxyproline
- BOC-D-PHE-OSU
- Boc-D-Valine
- 1-BOC-D-PYROGLUTAMIC ACID ETHYL ESTER
- Methyl N-(tert-butoxycarbonyl)-L-threoninate
- Boc-L-serine methyl ester
- BOC-GUANIDINE
- BOC-L-HYDROXYPROLINE METHYL ESTER,(2S,4R)-BOC 4-HYDROXYPROLINE METHYL ESTER,BOC-HYP-OME / BOC-L-HYDROXYPROLINE METHYL ESTER
- BOC-HYP(BZL)-OH
- 1-Boc-L-hydroxyproline ethyl ester
- N-Boc-trans-4-tosyloxy-L-proline methyl ester
- (2S, 4R)-BOC-GAMMA-MSO-PROLINE METHYL ESTER
- Boc-Hyp-OH
- BOC-CIS-HYDROXYPROLINE-OME
- L-Proline
- (2S,4R)-BOC-4-(2-NAPHTHYLMETHOXY)-PYRROLIDINE-2-CARBOXYLIC ACID
- BOC-HYP-OH DCHA
- (2S,4R)-BOC-4-(2-NAPHTHYLOXY)-PYRROLIDINE-2-CARBOXYLIC ACID