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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Amino Acids and Derivatives >  Alanine derivatives >  (S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide

(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide

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(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide Basic information

Product Name:
(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide
Synonyms:
  • 1-FLUORO-2,4-DINITROPHENYL-5-L-ALANINE AMIDE
  • Nα-(2,4-Dinitro-5-fluorophenyl)-L-alanine amide≥ 98% (HPLC)
  • NALPHA-(5-FLUORO-2,4-DINITROPHENYL)-L-ALANINAMIDE
  • N-ALPHA-(2,4-DINITRO-5-FLUOROPHENYL)-L-ALANINAMIDE
  • N-ALPHA-(2,4-DINITRO-5-FLUOROPHENYL)-L-ALANINE AMIDE
  • (2,4-Dinitro-5-fluorophenyl) L-Alaninamide
  • Marfey's Reagent, 99%, for chiral derivatization
  • Nalpha-(5-Fluoro-2,4-dinitrophenyl)-L-alaninamide [HPLC Labeling Reagent for e.e. Determination]
CAS:
95713-52-3
MF:
C9H9FN4O5
MW:
272.19
Product Categories:
  • proteinmod
  • Amino Acids & Derivatives
  • Aromatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Amino Group Labeling Reagents for HPLC
  • Analytical Chemistry
  • e.e. Determination (HPLC Labeling Reagents)
  • Enantiomer Excess & Absolute Configuration Determination
  • HPLC Labeling Reagents
  • UV Detection (HPLC Labeling Reagents)
Mol File:
95713-52-3.mol
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(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide Chemical Properties

Melting point:
229 °C
Boiling point:
544.5±50.0 °C(Predicted)
Density 
1.592±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
acetone: 10 mg/mL, clear, yellow
form 
powder
pka
15.61±0.50(Predicted)
color 
yellow to orange
optical activity
[α]20/D +56±2°, c = 1% in acetone
BRN 
6820069
InChIKey
NEPLBHLFDJOJGP-BYPYZUCNSA-N
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29242990

MSDS

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(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide Usage And Synthesis

Chemical Properties

Light yellow to yellow crystal or powder

Uses

FDAA was used as derivatizing reagent, in a study performed to understand unusual amino acids using reversed phase high performance liquid chromatography-electrospray ionization mass spectrometry (RPHPLC-ESI-MS).

Uses

N-α-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide is suitable for use for the derivatization of amino acids. glutamate and analine present in cell wall. Derivatized?D- and?L-amino acids can be resolved and quantitated by HPLC.

Uses

(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide can be used for chiral amino acid analysis.

General Description

Nα-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide (FDAA) is a chiral derivatizing agent (CDA), has high enantioselectivity but low sensitivity as compared to other CDAs. It is generally used to assign the stereochemistry of amino acids in trace amounts.

Biochem/physiol Actions

N-α-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide (FDAA) is a chiral derivatizing agent and is used routinely to improve the detection of underivatized amino acids in high performance liquid chromatography. Its usage is effective in separating stereoisomer.

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