GUANYLIN (HUMAN)
GUANYLIN (HUMAN) Basic information
- Product Name:
- GUANYLIN (HUMAN)
- Synonyms:
-
- GUANYLIN (HUMAN)
- H-PRO-GLY-THR-CYS-GLU-ILE-CYS-ALA-TYR-ALA-ALA-CYS-THR-GLY-CYS-OH
- H-PRO-GLY-THR-CYS-GLU-ILE-CYS-ALA-TYR-ALA-ALA-CYS-THR-GLY-CYS-OH(DISULFIDE BRIDGE: 4-12 AND 7-15)
- PGTCEICAYAACTGC (DISULFIDE BRIDGE: 4-12 AND 7-15)
- PRO-GLY-THR-CYS-GLU-ILE-CYS-ALA-TYR-ALA-ALA-CYS-THR-GLY-CYS
- H-Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH(Cys4-Cys12, Cys7-Cys15)
- PRO-GLY-THR-CYS-GLU-ILE-CYS-ALA-TYR-ALA-ALA-CYS-THR- GLY-CYS(DISULFIDE BRIDGE: CYS4-CYS12, CYS7-CYS15)
- L-Cysteine, L-prolylglycyl-L-threonyl-L-cysteinyl-L-α-glutamyl-L-isoleucyl-L-cysteinyl-L-alanyl-L-tyrosyl-L-alanyl-L-alanyl-L-cysteinyl-L-threonylglycyl-, cyclic (4→12),(7→15)-bis(disulfide)
- CAS:
- 183200-12-6
- MF:
- C58H87N15O21S4
- MW:
- 1458.66
- Product Categories:
-
- Peptide
- Mol File:
- 183200-12-6.mol
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GUANYLIN (HUMAN) Chemical Properties
- Boiling point:
- 1956.4±65.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- form
- White lyophilized powder.
- pka
- 2.96±0.70(Predicted)
- Water Solubility
- Soluble to 1 mg/ml in water
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GUANYLIN (HUMAN) Usage And Synthesis
Uses
Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism[1][2].
storage
Store at -20°C
References
[1] M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):947-51. DOI:10.1073/pnas.89.3.947
[2] J Be?towski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52(3):351-75. PMID:11596856
GUANYLIN (HUMAN)Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
GL Biochem (Shanghai) Ltd
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- 21-61263452 13641803416
- ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
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- 021-54306202 13764082696
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Chemsky (shanghai) International Co.,Ltd
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- 021-50135380
- shchemsky@sina.com
Cellmano Biotech Limited
- Tel
- 0551-65326643 18156095617
- info@cellmano.com