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D-Phenylglycinol

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D-Phenylglycinol Basic information

Product Name:
D-Phenylglycinol
Synonyms:
  • D-PHENYLGLYCINOL
  • d-plenylglycinol
  • D-PHG-OL
  • D-(-)2-AMINO-2-PHENYLETHANOL
  • D(-)-ALPHA-PHENYLGLYCINOL
  • D-(-)-A-PHENYLGLYCINOL
  • H-D-PHG-OL
  • BENZENEETHANOL, B-AMINO-, (BR)-
CAS:
56613-80-0
MF:
C8H11NO
MW:
137.18
EINECS:
260-287-5
Product Categories:
  • Amino Alcohols
  • chiral
  • Benzene derivatives
  • Amines
  • Aromatics
  • Catalyst
  • Chiral Reagent
  • Phenylglycine [Phg]
  • Amino Alcohols (Chiral)
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Pharmaceutical Intermediates
  • Alcohols and Derivatives
  • Synthetic Organic Chemistry
  • Amino alcohols
  • bc0001
Mol File:
56613-80-0.mol
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D-Phenylglycinol Chemical Properties

Melting point:
76-79 °C
alpha 
-25.5 º (c=6,MeOH)
Boiling point:
252.03°C (rough estimate)
Density 
1.0630 (rough estimate)
refractive index 
-29.5 ° (C=1, EtOH)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Aqueous Acid (Slightly, Sonicated), Chloroform (Sparingly, Heated), Methanol (Slightly)
form 
Crystalline Powder
pka
12.51±0.10(Predicted)
color 
White to yellow
optical activity
[α]24/D 31.7°, c = 0.76 in 1 M HCl
Water Solubility 
Slightly soluble in water.
Sensitive 
Air Sensitive
BRN 
2935848
InChIKey
IJXJGQCXFSSHNL-QMMMGPOBSA-N
CAS DataBase Reference
56613-80-0(CAS DataBase Reference)
NIST Chemistry Reference
(R)-(-)-2-phenylglycinol(56613-80-0)
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Safety Information

Hazard Codes 
C,T
Risk Statements 
34-36/37/38-23/24/25
Safety Statements 
22-24/25-45-36/37/39-26
WGK Germany 
3
2-10
HS Code 
29221980

MSDS

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D-Phenylglycinol Usage And Synthesis

Chemical Properties

white to light yellow crystal powder.

Uses

A chiral arylalkylamine used as organocatalysts. Used in the synthesis and chiral recognition properties of novel fluorescent chemosensors for amino acid.

Definition

ChEBI: (R)-(-)-2-Phenylglycinol is an aralkylamine.

Preparation

D-Phenylglycinol was synthesized by reducing D-phenylglycine using a sodium borohydride-iodine system. The best reaction conditions were using tetrahydrofuran as the solvent, a 1:2 ratio of D-phenylglycine to sodium borohydride, a hydrolysis temperature of 50°C, and a reaction time of 20 hours.

D-Phenylglycinol Preparation Products And Raw materials

Preparation Products

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