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(R)-(-)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL

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(R)-(-)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL Basic information

Product Name:
(R)-(-)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL
Synonyms:
  • (R)-(-)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL
  • (R)-(-)-1-PHENYL-2,2,2-TRIFLUOROETHANOL
  • (R)-(-)-2,2,2-TRIFLUORO-1-PHENYLETHANOL
  • (-)-PHENYL(TRIFLUOROMETHYL)CARBINOL
  • (-)-Phenyl(trifluoromethyl)carbinol, (R)-(-)-1-Phenyl-2,2,2-trifluoroethanol
  • (1R)-1-Phenyl-2,2,2-trifluoroethanol
  • (αR)-α-(Trifluoromethyl)benzenemethanol
  • (R)-(-)-ALPHA-(TRIFLUOROMETHYL)BENZYL AL COHOL, 99% (97% EE/GLC)
CAS:
10531-50-7
MF:
C8H7F3O
MW:
176.14
EINECS:
234-094-1
Mol File:
10531-50-7.mol
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(R)-(-)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL Chemical Properties

Melting point:
20 °C(lit.)
Boiling point:
73-76 °C9 mm Hg(lit.)
Density 
1.300 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.459(lit.)
Flash point:
189 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
clear liquid
pka
11.91±0.10(Predicted)
color 
Colorless to Almost colorless
CAS DataBase Reference
10531-50-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,C
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
10-23
HS Code 
29062990

MSDS

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(R)-(-)-ALPHA-(TRIFLUOROMETHYL)BENZYL ALCOHOL Usage And Synthesis

Uses

(R)?-?2,?2,?2-?Trifluoro-?1-?phenylethanol is a building block used in the synthesis of mesoporous metal-organic frameworks.

Purification Methods

Purify the chiral alcohols by fractional distillation preferably in a vacuum. [Morrison & Ridgeway Tetrahedron Lett 573 1969, NMR: Pirkle & Beare J Am Chem Soc 90 6250 1968.] The racemate [340-05-6] has b 52-54o/2mm,57-59o/2mm, 64-65o/5mm, d 4 20 1.293, n D 20 1.457, and the 2-carbobenzoyl derivative has m 137-138o [Mosher et al. J Am Chem Soc 78 4374 1956]. [Beilstein 6 IV 3043.]

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