- Product Name:
- CI 76535
- Product Categories:
- Aromatic Phenols
- Intermediates of Dyes and Pigments
- Phenoles and thiophenoles
- Building Blocks
- C6 to C8
- Chemical Synthesis
- Organic Building Blocks
- Oxygen Compounds
- Mol File:
2-Amino-5-nitrophenol Chemical Properties
- Melting point:
- 198-202 °C (dec.)(lit.)
- Boiling point:
- 322.46°C (rough estimate)
- 1.3617 (estimate)
- refractive index
- 1.6890 (rough estimate)
- Crystalline Powder
- Rust brown to brown
- Water Solubility
- CAS DataBase Reference
- 121-88-0(CAS DataBase Reference)
- 3 (Vol. 57) 1993
- EPA Substance Registry System
- 2-Amino-5-nitrophenol (121-88-0)
2-Amino-5-nitrophenol Usage And Synthesis
Brown to rust Crystalline powder
Reactant for:• ;Diazotation and coupling reactions1• ;Preparation of biologically and pharmacologically active molecules2
2-Amino-5-nitrophenol is used in hair dyes and as an intermediate in preparing azo dyes.
Brown amorphous granules or powder. Melting point 198-202°C.
Air & Water Reactions
Is slowly oxidized by air at room temperature. Insoluble in water.
2-Amino-5-nitrophenol is a reducing agent. Incompatible with strong oxidizing agents. Reacts slowly with oxygen in the air at room temperature. Stable at temperatures up to 140°F for two weeks when kept in the dark and under nitrogen. Stable under nitrogen for up to 24 weeks 77°F. Incompatible with strong bases . Incompatible with acid chlorides and acid anhydrides.
Flash point data for 2-Amino-5-nitrophenol are not available. 2-Amino-5-nitrophenol is probably combustible.
The potential carcinogenicity of 2-amino-5-nitrophenol was tested by NTP by oral administration (gavage) in corn oil to F344/N rats (100 and 200 mg/kg) and B6C3F1 mice (400 and 800 mg/kg) for 2 years. There was some evidence of carcinogenic activity in low-dose male rats, as indicated by increased incidence of acinar cell adenomas of the pancreas. No evidence of carcinogenic activity was found among female rats and the low-dose groups of male and female mice. The poor survival rates in the high-dose male rats and high-dose male and female mice reduced the sensitivity for detecting potential carcinogenic response.
Crystallise the phenol from water. [Beilstein 13 IV 803.]
- CHLOROPHOSPHONAZO III
- 2-AMINO-4-NITROPHENOL OEKANAL, 250 MG,2-Amino-4-nitrophenol;2-Hydroxy-5-nitroaniline; 3-Amino-4-hydroxynitrobenzene,2-AMINO-4-NITROPHENOL
- AMINO ACIDS
- 2-AMINO-3-NITROPHENOL OEKANAL, 250 MG,2-AMINO-3-NITROPHENOL
- PICRIC ACID
- Tris Base
- 2-Amino-5-nitrobenzoic acid
- 6-Aminocaproic acid