ChemicalBook > Product Catalog > Biochemical Engineering > Polypeptide > H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Basic information
- Product Name:
- H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
- Synonyms:
-
- ET-2 (HUMAN)
- ET-2 (HUMAN, PIG, DOG)
- H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
- H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH (DISULFIDE BRIDGE: 1-15 AND 3-11)
- ENDOTHELIN-II, HUMAN
- ENDOTHELIN 2
- ENDOTHELIN 2 HUMAN
- ENDOTHELIN-2 (HUMAN, CANINE)
- CAS:
- 123562-20-9
- MF:
- C115H160N26O32S4
- MW:
- 2546.92
- Product Categories:
-
- Cardiovescular
- Peptide
- AgonistsApplication Index
- Chymase and Related Products
- Cell Signaling Enzymes
- Endothelins
- Peptides for Cell Biology
- Endothelin receptor
- Mol File:
- 123562-20-9.mol
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H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Chemical Properties
- Density
- 1.286±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
- storage temp.
- −20°C
- solubility
- Soluble to 1 mg/ml in DMSO
- form
- powder
- color
- white
- Water Solubility
- Soluble in water (1 mg/ml)
- Sequence
- Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
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Safety Information
- Hazard Codes
- T+
- Risk Statements
- 26/27/28
- Safety Statements
- 28-36/37-45
- RIDADR
- UN 2811 6.1/PG 1
- WGK Germany
- 3
- F
- 3-10
- HazardClass
- 6.1
MSDS
- Language:English Provider:SigmaAldrich
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H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Usage And Synthesis
Uses
Endothelin-2 (49-69), human (Endothelin-2 (human, canine)) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
in vivo
Two distinct phases of pressor effects are typically seen in response to Endothelin-2: the early phase immediately follows the depressor response and dominates during the next 3-10 min, whereas the late pressor effect develops 10-20 min after the injection and lasts >1 hr[1].
storage
-20°C (desiccate)
References
[1] Grimshaw MJ, et al. Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. Eur J Immunol. 2002 Sep;32(9):2393-400. DOI:10.1002/1521-4141(200209)32:93.0.CO;2-4
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OHSupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
GL Biochem (Shanghai) Ltd
- Tel
- 21-61263452 13641803416
- ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Cellmano Biotech Limited
- Tel
- 0551-65326643 18156095617
- info@cellmano.com
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H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH(123562-20-9)Related Product Information
- Endothelin-1 (human, porcine)
- NITRIC OXIDE
- H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
- BIG ET-1 (1-38) (HUMAN)
- IRL-1038
- ENDOTHELIN (16-21)
- Serotonin hydrochloride
- HISTONE
- L(+)-Arginine
- Follicle stimulating hormone
- Histamine
- Luteinizing Hormone
- Prostaglandin E2
- RENNIN
- Bilirubin
- Bacterial endotoxin
- Endothelin antagonist
- H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH