2-Amino-3,5-dibromobenzoic acid Chemical Properties

Melting point:

235-236 °C(lit.)

Boiling point:

367.6±42.0 °C(Predicted)

Density 

2.158±0.06 g/cm3(Predicted)

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

4.16±0.10(Predicted)

form 

Powder

color 

White to beige

BRN 

779291

CAS DataBase Reference

609-85-8(CAS DataBase Reference)

NIST Chemistry Reference

3,5-Dibromoanthranilic acid(609-85-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-37/38-36

Safety Statements 

26-37/39

WGK Germany 

3

HS Code 

29224985

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Amino-3,5-dibromobenzoic acid Usage And Synthesis

Synthesis

A solution of bromine (7.2 g, 2 mL, 40 mmol) in 47 mL glacial acetic acid was added dropwise to sodium 2-aminobenzoate (6.4 g, 40 mmol) in 32 mL of glacial acetic acid  at 15 °С and the mixture was stirred for 1 h at the same temperature. The product  was filtered off, washed with benzene and dried in the dark. The bromobenzoic acids  containing mixture (0.5 g) was added to 10 mL of boiling water followed by the  addition of 1.3 mL of concentrated hydrochloric acid and hot filtration under vacuum.  The insoluble material contained 2-amino-3,5-dibromobenzoic acid, whereas 2- amino-5-bromobenzoic acid precipitated upon cooling of the filtrate. IR (suspension in nujol, cm−1 ): 3469, 3364,  1682, 1600, 1564, 1538, 1454, 1421, 1378, 1328, 1307, 1226, 1063, 902, 882, 790,  711, 691, 591, 543.

Chemical Properties

White to light yellow crystal powder

2-Amino-3,5-dibromobenzoic acid(609-85-8)Related Product Information

• 2-Amino-4-bromobenzoic acid
• Glycine
• 4-Aminobenzoic acid
• 4-Dimethylaminobenzoic acid
• 6-Aminocaproic acid
• 3,5-Dibromobenzoic acid
• 2-Amino-5-bromobenzoic acid
• Tris(hydroxymethyl)aminomethane
• ALTRENOGEST
• trans-4-Aminocyclohexanol hydrochloride
• 4-ACETAMIDOCYCLOHEXANOL
• TRANS-4-ACETAMIDOCYCLOHEXANOL
• 4α-Aminocyclohexan-1α-ol
• IMP. D (EP) AS HYDROCHLORIDE: CIS-4-[(2-AMINO-3,5-DIBROMOBENZYL)AMINO]CYCLOHEXANOL HYDROCHLORIDE
• AMbroxol hydrochloride iMpurity C
• AmBroxol Impurity 11
• 4-aminocyclohexan-1-ol
• AMbroxol hydrochloride iMpurity B