4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Chemical Properties

Boiling point:

529.8±50.0 °C(Predicted)

Density 

1.150±0.06 g/cm3(Predicted)

storage temp. 

Store at RT

solubility 

Soluble to 100 mM in ethanol and to 100 mM in DMSO

form 

Powder

pka

pKa 8.75 (Uncertain)

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Usage And Synthesis

Uses

SDZ 21009 is a 5-HT1A/1B antagonist.

Definition

ChEBI: 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid propan-2-yl ester is an isopropyl ester and an indolyl carboxylate ester.

Biological Activity

β -adrenoceptor and 5-HT 1A/1B receptor antagonist. pK B /pA 2 values are 8.3 and 8.0 for 5-HT 1A and 5-HT 1B receptors respectively. Centrally active following systemic administration in vivo .

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER(39731-05-0)Related Product Information

• 4-Methoxy-1H-indole-2-carboxylic acid
• rac Mepindolol-d7
• 4-Hydroxy-2-methylindole
• METHYL 4-METHOXY-2-INDOLECARBOXYLATE
• 4-methoxy-2-methyl-1H-indole
• 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
• Pindolol