Alkannin Chemical Properties

Melting point:

149°

alpha 

20Cd -165° (benzene); -226° (chloroform). Also reported as -254 ± 7° (chloroform) (Toribara)

Boiling point:

567.4±50.0 °C(Predicted)

Density 

1.373±0.06 g/cm3(Predicted)

storage temp. 

-20°C, protect from light

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

powder

pka

7.34±0.20(Predicted)

color 

Purple

Safety Information

Toxicity

LD50 in male, female mice, rats (g/kg): 3.0 ± 1.0; 3.1 ± 0.1; >1.0 orally (Majlathova)

Alkannin Usage And Synthesis

Uses

Alkannin is a enantiomeric dye from Alkanna tinctoria and Lithospermum erythrorhizon, which has known as dyestuff, wound healing, anti-inflammatory, anti-bacterial and anti-tumor substances.

Uses

Alkannin (cas# 23444-65-7) inhibits proliferation, migration and invasion of human Huh7 and Hep3B2.1-7 hepatocellular carcinoma cells via regulation of miR92a. It is also useful in the application of macromolecular crowding to investigate naphthoquinones shikonin, naphthazarin and related analogs for treatment of dermal scars in human.

Definition

ChEBI: Alkannin is a hydroxy-1,4-naphthoquinone.

Alkannin(517-88-4)Related Product Information

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