2-TRIFLUOROMETHYL-2-PROPANOL Chemical Properties

Melting point:

53℃

Boiling point:

83 °C (lit.)

Density 

1.17 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.3335(lit.)

Flash point:

59 °F

pka

12.60±0.29(Predicted)

form 

clear liquid

color 

Colorless to Almost colorless

BRN 

1736196

CAS DataBase Reference

507-52-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

F

Risk Statements 

11

Safety Statements 

16-23-36

RIDADR 

1987

WGK Germany 

3

Hazard Note 

Flammable

HazardClass 

3

PackingGroup 

II

HS Code 

2905599890

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-TRIFLUOROMETHYL-2-PROPANOL Usage And Synthesis

Uses

2-Trifluoromethyl-2-propanol may be employed as a solvent for the preparation of [¹⁸F]fluorothymidine. It may also be used in the synthesis of [2-(trifluoromethyl)-2-propyl nitrate] through nitration in nitric acid/trifluoroacetic anhydride.

General Description

2-Trifluoromethyl-2-propanol is a fluorinated aliphatic alcohol. It can be prepared by reacting methyllithium, trifluoroacetone and trifluorovinyl bromide in ether. This can also be synthesized from the reaction between methylmagnesium bromide and 1,1,1-trifluoroacetone in ether.

2-TRIFLUOROMETHYL-2-PROPANOL(507-52-8)Related Product Information

• 4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE
• 3-HYDROXY-3-METHYL-4,4,4-TRIFLUOROBUTYRIC ACID
• HEXAFLUORO-2-METHYLISOPROPANOL
• 1,1,1,3,3,3-HEXAFLUORO-2-PHENYL-2-PROPANOL
• HEXAFLUORO-2-(P-TOLYL)ISOPROPANOL
• (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
• 3,3-BIS(TRIFLUOROMETHYL)-3-HYDROXYPROPIONIC ACID
• 1,4-BIS(2-HYDROXYHEXAFLUOROISOPROPYL)BENZENE
• 2-METHOXY-2-PHENYL-3,3,3-TRIFLUOROPROPIONITRILE
• 2-TRIFLUOROMETHYL-2-PROPANOL
• 1,3-BIS(2-HYDROXYHEXAFLUOROISOPROPYL)BENZENE
• 1,1,1-TRIFLUOROACETONE CYANOHYDRIN
• 3-(3'-TRIFLUOROMETHYL PHENYL) PROPANOL
• PERFLUORO-TERT-BUTANOL
• tert-Butanol
• 2-(2,5-Dimethylphenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
• BIS[ALPHA,ALPHA-BIS(TRIFLUOROMETHYL)BENZENEMETHANOLATO]DIPHENYLSULFUR
• 4,4'-BIS(2-HYDROXYHEXAFLUOROISOPROPYL)BIPHENYL