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LOSARTAN-D4

Basic information Safety Supplier Related

LOSARTAN-D4 Basic information

Product Name:
LOSARTAN-D4
Synonyms:
  • Reaxys ID: 18951469
  • 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5yl)[1,1'-biphenyl-d4]-4-yl]Methyl]-1H-iMidazole-5-Methanol
  • Cozaar-d4
  • MK-954-d4
  • LOSARTAN-D4
  • 2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl-2,3,5,6-d4]methyl]-1H-imidazole-5-methanol
  • [2H4]-Losartan
  • DuP-753 D4
CAS:
1030937-27-9
MF:
C22H19ClD4N6O
MW:
426.94
Product Categories:
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
Mol File:
Mol File
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LOSARTAN-D4 Chemical Properties

Melting point:
184-190?C
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly),Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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LOSARTAN-D4 Usage And Synthesis

Description

Losartan-D4 is a deuterium-labeled version of Losartan, which is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM. Losartan is an antagonist of the angiotensin (AT) II receptor subtype AT1 with a K i value of 5-20 nM. 

Chemical Properties

White Solid

Uses

A labelled version of Losartan, a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.

Uses

As a labelled version of Losartan, Losartan-d4 can be used as a nonpeptide angiotensin II AT1-receptor antagonist and Antihypertensive.

Uses

Losartan-d4 can be intended for use as an internal standard for the quantification of Losartan by GC- or LC-mass spectrometry.

LOSARTAN-D4Supplier

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