Cassiaside B2 Chemical Properties

Boiling point:

1223.3±65.0 °C(Predicted)

Density 

1.77±0.1 g/cm3(Predicted)

pka

6.06±0.40(Predicted)

Cassiaside B2 Usage And Synthesis

Uses

Cassiaside B2 is a protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A) inhibitor. Cassiaside B2 possesses antiallergic and is a 5-HT2C receptor agonist[1][2].[3]..

Definition

ChEBI: Cassiaside B2 is an oligosaccharide.

References

[1] Pradeep Paudel, et al. Rubrofusarin as a Dual Protein Tyrosine Phosphate 1B and Human Monoamine Oxidase-A Inhibitor: An in Vitro and in Silico Study. ACS Omega. 2019 Jul 3;4(7):11621-11630. DOI:10.1021/acsomega.9b01433
[2] S Kitanaka, et al. Antiallergic agent from natural sources. Structures and inhibitory effect of histamine release of naphthopyrone glycosides from seeds of Cassia obtusifolia L. Chem Pharm Bull (Tokyo). 1998 Oct;46(10):1650-2. DOI:10.1248/cpb.46.1650
[3] Heidi Yuen, et al. Mechanisms of Action of Cassiae Semen for Weight Management: A Computational Molecular Docking Study of Serotonin Receptor 5-HT2C. Int J Mol Sci. 2020 Feb 16;21(4):1326. DOI:10.3390/ijms21041326

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