Basic information Safety Supplier Related

E3 ligase Ligand-Linker Conjugates 17

Basic information Safety Supplier Related

E3 ligase Ligand-Linker Conjugates 17 Basic information

Product Name:
E3 ligase Ligand-Linker Conjugates 17
Synonyms:
  • E3 ligase Ligand-Linker Conjugates 17
  • E3 Ligase Ligand-Linker Conjugates 20 (TFA)
  • Cereblon Ligand -Linker Conjugates 2 TFA
  • Pomalidomide Related Compound 6 Triflate
  • N-(8-Aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate
  • N-(8-aminooctyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide trifluoroacetate
  • Thalidomide-O-amido-C8-NH2 trifluoroacetate
CAS:
1950635-16-1
MF:
C25H31F3N4O8
MW:
572.54
Mol File:
1950635-16-1.mol
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E3 ligase Ligand-Linker Conjugates 17 Chemical Properties

storage temp. 
2-8°C
form 
Solid
color 
White to off-white
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E3 ligase Ligand-Linker Conjugates 17 Usage And Synthesis

Uses

Thalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

IC 50

Cereblon

References

[1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

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