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Phthalylglycyl chloride

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Phthalylglycyl chloride Basic information

Product Name:
Phthalylglycyl chloride
Synonyms:
  • Phthalyl-glycyl chloride ,98%
  • (1,3-Dioxo-2H-isoindole-2-yl)acetyl chloride
  • 1,3-Dihydro-1,3-dioxo-2H-isoindole-2-acetic acid chloride
  • 2-(Phthalimidyl)acetyl chloride
  • 2-Phthalimidylacetic acid chloride
  • N-(2-Chloro-2-oxoethyl)phthalimide
  • N,N-Phthaloylglycine chloride
  • 2-(1,3-dioxoisoindolin-2-yl) acetyl chloride
CAS:
6780-38-7
MF:
C10H6ClNO3
MW:
223.61
EINECS:
229-840-8
Product Categories:
  • Acid Halides
  • Carbonyl Compounds
  • pharmacetical
  • Organic Building Blocks
  • Acid Halides
  • Building Blocks
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • Heterocycle-other series
Mol File:
6780-38-7.mol
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Phthalylglycyl chloride Chemical Properties

Melting point:
84-85 °C
Boiling point:
190-192 °C(Press: 15 Torr)
Density 
1.504±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Chloroform, Dichloromethane
form 
Solid
pka
-2.56±0.20(Predicted)
color 
White
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Safety Information

Hazard Codes 
T
Risk Statements 
25-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2923 8/PG 3
WGK Germany 
3
HazardClass 
IRRITANT

MSDS

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Phthalylglycyl chloride Usage And Synthesis

Chemical Properties

slight yellow to white crystalline powder

Uses

Reactant involved in:• ;Synthesis of selenium-containing amino acid analogs with bactericidal and antifungal activity1• ;Photoinduced single electron transfer cyclization for preparation of cyclic peptides2• ;Arndt-Eistert synthesis3• ;Mitsunobu and arbuzov-type multicomponent pathway4• ;Remote C-H bond functionalization5• ;Amido-alkylation for synthesis of benzofuran derivatives6

Uses

Phthalylglycyl chloride can be used in the synthesis of N-Phthalimidoacetyl-β-phenylethylamnine.

General Description

Phthalylglycyl chloride can be synthesized via reaction of phthalyl-glycine with thionyl chloride.

Phthalylglycyl chlorideSupplier

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