1,2-BISMALEIMIDOETHANE
1,2-BISMALEIMIDOETHANE Basic information
- Product Name:
- 1,2-BISMALEIMIDOETHANE
- Synonyms:
-
- 1,1'-Ethylenebis(3-pyrroline-2,5-dione)
- 1,1'-Ethylenebis[1H-pyrrole-2,5-dione]
- N,N'-Ethylenebis(maleinimide)
- 1-(2-maleimidoethyl)-3-pyrroline-2,5-quinone
- 1-[2-(2,5-dioxopyrrol-1-yl)ethyl]pyrrole-2,5-dione
- 1,2-DiMaleiMidoethane
- 1,1'-(1,2-Ethanediyl)bis-1H-pyrrole-2,5-dione
- NSC 41127
- CAS:
- 5132-30-9
- MF:
- C10H8N2O4
- MW:
- 220.18
- Product Categories:
-
- pharmacetical
- Maleimide Derivatives
- N-Substituted Maleimides
- N-Substituted Maleimides, Succinimides & Phthalimides
- Cross Linking Reagents
- MTS & Sulfhydryl Active Reagents
- Mol File:
- 5132-30-9.mol
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1,2-BISMALEIMIDOETHANE Chemical Properties
- Melting point:
- 193-194°C
- Boiling point:
- 428.3±28.0 °C(Predicted)
- Density
- 1.510±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform
- form
- Solid
- pka
- -2.11±0.20(Predicted)
- color
- Off White
- CAS DataBase Reference
- 5132-30-9(CAS DataBase Reference)
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1,2-BISMALEIMIDOETHANE Usage And Synthesis
Chemical Properties
Off White Solid
Uses
A short, sulfhydryl reactive homobifunctional crosslinking reagent.
General Description
BMOE, BMB and BMH are homobifunctional, maleimide crosslinkers for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e., oligomerization) or protein interactions. Because BMOE, BMB and BMH have the same reactivity but differ in length, the relative success of these three reagents in forming crosslinks between sites in a protein oligomer or interaction can assist in determining intra- and intermolecular distances.
1,2-BISMALEIMIDOETHANESupplier
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