(6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE Chemical Properties

Boiling point:

506.6±60.0 °C(Predicted)

Density 

1.89±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,2-8°C

pka

5.05(at 25℃)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

WGK Germany 

3

RTECS 

UO3516500

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich

(6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE Usage And Synthesis

Chemical Properties

Pk'5.05. UV maximum absorption (0.1 mol/L hydrochloric acid): 265 nm (ε14000). Sapropterin Dihydrochloride: C9H15N5O3?2HCl.[69056-38-8]. White crystal or crystalline powder, odorless, slightly acidic taste. Extremely soluble in water, more difficult to dissolve in methanol, very difficult to dissolve in ethanol, a few insoluble in ether. Melting point 245～246°C (decomposition). [α]D25-6.81.(C=0.665, 0.1mol/L hydrochloric acid).UV max absorption(2mol/L hydrochloric acid): 264nm(ε16770).

Uses

Treatment of mild-to-moderate phenylketonuria (PKU).

Definition

ChEBI: Sapropterin is a tetrahydropterin that is 2-amino-5,6,7,8-tetrahydropteridin-4(3H)-one in which a hydrogen at position 6 is substituted by a 1,2-dihydroxypropyl group (6R,1'R,2'S-enantiomer). It has a role as a coenzyme, a diagnostic agent, a human metabolite and a cofactor.

IC 50

Human Endogenous Metabolite

(6R,S)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE(62989-33-7)Related Product Information

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