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Canagliflozin-10

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Canagliflozin-10 Basic information

Product Name:
Canagliflozin-10
Synonyms:
  • (2R,3R,4R,5R)-2-((R)-1,2-dihydroxyethyl)-5-(3-((5-(4- fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl) tetrahydrofuran-3,4-diol
  • Canagliflozin impurity 9/(2R,3R,4R,5R)-2-((R)-1,2-dihydroxyethyl)-5-(3-((5-(4- fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl) tetrahydrofuran-3,4-diol
  • D-Galactitol, 1,4-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-
  • Canagliflozin Furanose Form (Mixture of Anomers)
  • canagliflozin impurities613
  • canagliflozin impurities3
  • Canagliflozin-10
CAS:
2161394-94-9
MF:
C24H25FO5S
MW:
444.52
Mol File:
2161394-94-9.mol
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Canagliflozin-10 Chemical Properties

Melting point:
>53°C (dec)
Boiling point:
673.5±55.0 °C(Predicted)
Density 
1.375±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
pka
13.56±0.70(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Canagliflozin-10 Usage And Synthesis

Uses

1-C-[3-[[5-(4-Fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucose is an intermediate used in the synthesis of Canagliflozin (C175190). Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor; Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.

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