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2-amino-N-(2-methylphenyl)-5-thiazolecarboxamide

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2-amino-N-(2-methylphenyl)-5-thiazolecarboxamide Basic information

Product Name:
2-amino-N-(2-methylphenyl)-5-thiazolecarboxamide
Synonyms:
  • 2-amino-N-(2-methylphenyl)-5-thiazolecarboxamide
  • 5-Thiazolecarboxamide, 2-amino-N-(2-methylphenyl)-
  • 2-amino-N-(o-tolyl)thiazole-5-carboxamide? (Dasatinib Impurity)
CAS:
1184914-03-1
MF:
C11H11N3OS
MW:
233.29
Mol File:
1184914-03-1.mol
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2-amino-N-(2-methylphenyl)-5-thiazolecarboxamide Chemical Properties

Boiling point:
336.9±25.0 °C(Predicted)
Density 
1.375±0.06 g/cm3(Predicted)
pka
12.02±0.70(Predicted)
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2-amino-N-(2-methylphenyl)-5-thiazolecarboxamide Usage And Synthesis

Uses

2-Amino-N-(o-tolyl)-thiazole-5-carboxamide is an impurity of the anti-cancer drug Dasatinib (D193600). Dasatinib is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic.

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