OXYMORPHONE HCL NARCOTIC ANALGESIC
OXYMORPHONE HCL NARCOTIC ANALGESIC Basic information
- Product Name:
- OXYMORPHONE HCL NARCOTIC ANALGESIC
- Synonyms:
-
- OXYMORPHONE HCL NARCOTIC ANALGESIC
- 3,14-dihydroxy-4,5-alpha-epoxy-17-methyl-morphinan-6-onhydrochloride
- 4,5-alpha-epoxy-3,14-dihydroxy-17-methylmorphinan-6-onehydrochloride
- morphinan-6-one,4,5-epoxy-3,14-dihydroxy-17-methyl-,hydrochloride,(5-alpha
- numorphanhydrochloride
- oxymorphinonehydrochloride
- (5alpha)-4,5-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride
- OxyMorphone HCl
- CAS:
- 357-07-3
- MF:
- C17H21ClNO4
- MW:
- 338.80594
- EINECS:
- 206-610-5
- Mol File:
- 357-07-3.mol
More
Less
OXYMORPHONE HCL NARCOTIC ANALGESIC Chemical Properties
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- color
- Yellowish-tan powder
- Stability:
- Hygroscopic
More
Less
More
Less
OXYMORPHONE HCL NARCOTIC ANALGESIC Usage And Synthesis
Uses
Analgesic (narcotic).
Definition
ChEBI: Oxymorphone hydrochloride is a member of phenanthrenes.
brand name
Numorphan (Endo); Opana (Endo).
Clinical Use
Oxymorphone is a potent μ agonist (10 times greater than morphine) that is used to treat severe pain. It is used by intramuscular, subcutaneous, intravenous, and rectal routes of administration. The intramuscular dose of oxymorphone (1 mg) has a half-life of 3 to 4 hours. It is a Schedule II drug. Oxymorphone, because of its 14-hydroxy group, has low antitussive activity.
Safety Profile
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl.