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Cabozantinib impurity DX2

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Cabozantinib impurity DX2 Basic information

Product Name:
Cabozantinib impurity DX2
Synonyms:
  • N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluoro-2-hydroxyphenyl)-1,1-cyclopropanedicarboxamide
  • Cabozantinib impurity DX2
  • Cabozantinib impurity 65
  • 1,1-Cyclopropanedicarboxamide, N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluoro-2-hydroxyphenyl)-
  • N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-2-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
  • Cabozantinib Metabolite M9
  • Cabozantinib Impurity 78
  • N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-2-hydroxyphenyl)cyclopropane-1,1-dicarboxamide? (Cabozantinib Impurity)
CAS:
1628530-38-0
MF:
C28H24FN3O6
MW:
517.51
Mol File:
1628530-38-0.mol
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Cabozantinib impurity DX2 Chemical Properties

Boiling point:
781.8±60.0 °C(Predicted)
Density 
1.447±0.06 g/cm3(Predicted)
pka
8.42±0.40(Predicted)
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Cabozantinib impurity DX2 Usage And Synthesis

Uses

2-??Hydroxy Cabozantinib is a metabolite of cabozantinib (CAS# 849217-68-1), which is a tyrosine kinase inhibitor and an anticancer drug used in the treatment of thyroid cancer, renal cell carcinoma and hepatocellular carcinoma.

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