3-Fluorophenylacetonitrile Chemical Properties

Melting point:

21 °C

Boiling point:

113-114 °C18 mm Hg(lit.)

Density 

1.163 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.502(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

form 

powder to lump to clear liquid

color 

White or Colorles to Yellow to Orange

Specific Gravity

1.163

BRN 

1861071

Exposure limits

NIOSH: IDLH 25 mg/m3

CAS DataBase Reference

501-00-8(CAS DataBase Reference)

NIST Chemistry Reference

Benzeneacetonitrile, 3-fluoro-(501-00-8)

EPA Substance Registry System

Benzeneacetonitrile, 3-fluoro- (501-00-8)

Safety Information

Hazard Codes 

Xn,Xi,T

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-37/39-24/25-36

RIDADR 

3276

WGK Germany 

3

Hazard Note 

Toxic

TSCA 

T

HazardClass 

6.1

PackingGroup 

III

HS Code 

29269090

MSDS

• Language:English Provider:3-Fluorobenzeneacetonitrile
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Fluorophenylacetonitrile Usage And Synthesis

Chemical Properties

clear light yellow to slightly brown liquid

Uses

3-Fluorophenylacetonitrile is a phenylacetonitrile derivative that is mainly used in pharmaceutical manufacturing or organic synthesis. It is used as a pharmaceutical intermediate for Lemborexant. The drug is a dual receptor orexin antagonist (DORA) approved for the treatment of primary insomnia.

3-Fluorophenylacetonitrile(501-00-8)Related Product Information

• Copper(I) Cyanide
• Transfluthrin
• 3-NITROPHENYLACETONITRILE
• Florfenicol
• 3-Fluoroanisole
• 1,3-Difluorobenzene
• (3-Methoxyphenyl)acetonitrile
• Iminodiacetonitrile
• 3-Fluorophenethylamine
• 3'-Fluoroacetophenone
• POTASSIUM CYANIDE
• 2,5-DIFLUOROPHENYLACETONITRILE
• 2,3,4,5,6-PENTAFLUOROPHENYLACETONITRILE
• 3-FLUORO-5-(TRIFLUOROMETHYL)PHENYLACETONITRILE
• 3,4-Difluorophenylacetonitrile
• 5-FLUORO-2-NITROPHENYLACETONITRILE
• 3-FLUORO-4-METHOXYPHENYLACETONITRILE
• 2,4,5-Trifluorophenylacetonitrile