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Schisandrin A

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Schisandrin A Basic information

Product Name:
Schisandrin A
Synonyms:
  • SCHISANDRIN A (DEOXYSCHISANDRIN)
  • SCHISANDRA CHINENSIS PLANT EXTRACT 9+% SCHISANDRINS
  • SCHISANDRA CHINENSIS PLANT EXTRACT 5+% SCHISANDRINS
  • SCHISANDRA PLANT EXTRACT
  • SCHISANDRA BERRY POWDER
  • SCHISANDRIN A, (DEOXYSCHISANDRIN) 98% BY HPLC
  • SCHISANDRA CHINENSIS PLANT EXTRACT 2+% SCHISANDRINS
  • DEOXYSCHIZANDRIN90%,99%
CAS:
61281-38-7
MF:
C24H32O6
MW:
416.51
Product Categories:
  • Miscellaneous Natural Products
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
61281-38-7.mol
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Schisandrin A Chemical Properties

Melting point:
116-117 °C
Boiling point:
544.2±50.0 °C(Predicted)
Density 
1.080±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
powder
color 
White to Off-White
LogP
5.870 (est)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
HP1595000
HS Code 
29093090
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Schisandrin A Usage And Synthesis

Description

Schisandrin A is a lignan that has been found in Schisandra and has diverse biological activities. It binds to adiponectin receptor 2 (IC50 = 3.2 μM). Schisandrin A (10, 20, and 50 μM) reduces LPS-induced production of nitric oxide (NO), IL-6, and TNF-α and apoptosis in primary mouse microglial cells. It reverses P-glycoprotein-mediated doxorubicin resistance in MCF-7/dox cells when used at a concentration of 20 μM. Schisandrin A (4, 12, and 36 mg/kg) reverses short-term and spatial memory deficits, as well as decreases in cerebral superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities induced by amyloid β (1-42) (Aβ42; ) in a mouse model of Alzheimer’s disease.

Chemical Properties

White powder

Uses

Schizandrin A is an extract from Schisandra chinesis. a dibenzocyclooctadiene lignan with antiinflammatory activity.

Schisandrin ASupplier

CHENGDU JINMAIRUI BIO-TECHNOLOGY CO.LTD Gold
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028-83133020 18280298385
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Adamas Reagent, Ltd.
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400-6009262 16621234537
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zhangsn@titansci.com
Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
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cwb1@biopurify.cn
Finetech Industry Limited
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027-87465837 19945049750
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Shanghai Macklin Biochemical Co.,Ltd.
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15221275939 15221275939
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shenlinxing@macklin.cn